Explore TFF1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T38159
|
| Target Name |
TFF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7031
|
| Gene ID |
100170654 (Felis catus), 100301237 (Bos taurus), 100423966 (Macaca mulatta), 100629635 (Equus caballus)
117270 (Rattus norvegicus), 21784 (Mus musculus), 403491 (Canis lupus familiaris), 7031 (Homo sapiens)
|
| Target Alternative Names |
BCEI,Bcei,Breast cancer estrogen-inducible protein,D21S21,HP1.A,HPS2,PNR-2,PS2,Polypeptide P1.A (hP1.A),Protein pS2,Ps2,TFF1,Tff1,Trefoil factor 1,pNR-2,pS2
|
| Uniprot Accession |
Q63467,Q08423,Q863T4,P04155
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Disease |
cancer
|
| Gene Ensembl |
ENSBTAG00000048276, ENSMMUG00000050587, ENSECAG00000018260, ENSMUSG00000024032, ENSCAFG00845030496, ENSG00000160182
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of TFF1 cDNA Clones/ORF Plasmid
TFF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7031 | Pre-made Human TFF1/pS2/BCEI siRNA oligo Duplex | 7031 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117270 | Pre-made Rat Tff1/Ps2 siRNA oligo Duplex | 117270 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21784 | Pre-made Mouse Tff1/PS2/Bcei siRNA oligo Duplex | 21784 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100423966 | Pre-made Cynomolgus/Rhesus macaque TFF1 siRNA oligo Duplex | 100423966 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100170654 | Pre-made Cat/Feline TFF1 siRNA oligo Duplex | 100170654 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403491 | Pre-made Dog/Canine TFF1 siRNA oligo Duplex | 403491 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100301237 | Pre-made Bovines/Cattle TFF1 siRNA oligo Duplex | 100301237 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100629635 | Pre-made Equine/Horse TFF1 siRNA oligo Duplex | 100629635 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TFF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T38159-Ab | Human | Anti-Human TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T38159-Ab | Rat | Anti-Rat TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T38159-Ab | Mouse | Anti-Mouse TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T38159-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T38159-Ab | Cat/Feline | Anti-Cat/Feline TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T38159-Ab | Dog/Canine | Anti-Dog/Canine TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T38159-Ab | Bovines/Cattle | Anti-Bovines/Cattle TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T38159-Ab | Equine/Horse | Anti-Equine/Horse TFF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
TFF1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T38159-Ag | Human | Human TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T38159-Ag | Rat | Rat TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T38159-Ag | Mouse | Mouse TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T38159-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T38159-Ag | Cat/Feline | Cat/Feline TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T38159-Ag | Dog/Canine | Dog/Canine TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T38159-Ag | Bovines/Cattle | Bovines/Cattle TFF1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T38159-Ag | Equine/Horse | Equine/Horse TFF1 recombinant protein | Mammalian cell | Detail |
