IRF3 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore IRF3 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]

Target ID	GM-T38017
Target Name	IRF3
Gene Group ldentifer （Target Gene ID in Homo species)	3661
Gene ID	100055868 (Equus caballus), 101095934 (Felis catus), 292892 (Rattus norvegicus), 3661 (Homo sapiens) 476412 (Canis lupus familiaris), 516979 (Bos taurus), 54131 (Mus musculus), 718970 (Macaca mulatta)
Target Alternative Names	C920001K05Rik,IIAE7,IRF-3,IRF3,Interferon regulatory factor 3,Irf3
Uniprot Accession	Q14653,Q4JF28,P70671
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease	cancer
Disease from KEGG	Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, RIG-I-like receptor signaling pathway, Alcoholic liver disease, Pertussis, Yersinia infection, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Lipid and atherosclerosis
Gene Ensembl	ENSECAG00000018265, ENSG00000126456, ENSCAFG00845023315, ENSBTAG00000006633, ENSMUSG00000003184, ENSMMUG00000022735

Pre-made viral vector of IRF3 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP003714	Human IRF3/IIAE7 Lentivirus plasmid	NM_001197122	3661	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC001562	Human IRF3/IIAE7 Mammalian (Non-Viral Vector) plasmid	NM_001571.6	3661	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMPC004927	Human IRF3/IIAE7 Mammalian (Non-Viral Vector) plasmid	NM_001571	3661	Human	Mammalian (Non-Viral Vector) plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP003714	Human IRF3/IIAE7 Lentivirus particle	NM_001197122	3661	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD000280	Mouse Irf3/C920001K05Rik/IRF-3 Adenovirus plasmid	NM_016849.4	54131	Mouse	Adenovirus plasmid	Null	Null	CMV	Detail
vGMAD000280	Mouse Irf3/C920001K05Rik/IRF-3 Adenovirus particle	NM_016849.4	54131	Mouse	Adenovirus particle	Null	Null	CMV	Detail

IRF3 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo3661	Pre-made Human IRF3/IIAE7 siRNA oligo Duplex	3661	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo292892	Pre-made Rat Irf3 siRNA oligo Duplex	292892	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo54131	Pre-made Mouse Irf3/IRF-3/C920001K05Rik siRNA oligo Duplex	54131	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo718970	Pre-made Cynomolgus/Rhesus macaque IRF3 siRNA oligo Duplex	718970	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101095934	Pre-made Cat/Feline IRF3 siRNA oligo Duplex	101095934	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo476412	Pre-made Dog/Canine IRF3 siRNA oligo Duplex	476412	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo516979	Pre-made Bovines/Cattle IRF3 siRNA oligo Duplex	516979	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100055868	Pre-made Equine/Horse IRF3 siRNA oligo Duplex	100055868	Equine/Horse	In-vitro grade; in-vivo grade	Detail

IRF3 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T38017-Ab	Human	Anti-Human IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T38017-Ab	Rat	Anti-Rat IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T38017-Ab	Mouse	Anti-Mouse IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T38017-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T38017-Ab	Cat/Feline	Anti-Cat/Feline IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T38017-Ab	Dog/Canine	Anti-Dog/Canine IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T38017-Ab	Bovines/Cattle	Anti-Bovines/Cattle IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T38017-Ab	Equine/Horse	Anti-Equine/Horse IRF3 monoclonal antibody	mab	Therapeutics Target antibody	Detail

IRF3 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T38017-Ag	Human	Human IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T38017-Ag	Rat	Rat IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T38017-Ag	Mouse	Mouse IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T38017-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T38017-Ag	Cat/Feline	Cat/Feline IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T38017-Ag	Dog/Canine	Dog/Canine IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T38017-Ag	Bovines/Cattle	Bovines/Cattle IRF3 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T38017-Ag	Equine/Horse	Equine/Horse IRF3 recombinant protein	Mammalian cell	Detail