Explore CD22 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T37539
|
| Target Name |
CD22
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
933
|
| Gene ID |
100146402 (Equus caballus), 101081100 (Felis catus), 106994739 (Macaca mulatta), 12483 (Mus musculus)
308501 (Rattus norvegicus), 476485 (Canis lupus familiaris), 514582 (Bos taurus), 933 (Homo sapiens)
|
| Target Alternative Names |
A530093D23,B-cell receptor CD22,B-lymphocyte cell adhesion molecule (BL-CAM),CD22,Cd22,Lyb-8,Lyb8,SIGLEC-2,SIGLEC2,Sialic acid-binding Ig-like lectin 2 (Siglec-2),T-cell surface antigen Leu-14
|
| Uniprot Accession |
P35329,P20273
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cell adhesion molecules, Hematopoietic cell lineage, B cell receptor signaling pathway
|
| Gene Ensembl |
ENSECAG00000021515, ENSMMUG00000017621, ENSMUSG00000030577, ENSCAFG00845003158, ENSBTAG00000011887, ENSG00000012124
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
CD22 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo933 | Pre-made Human CD22/SIGLEC2/SIGLEC-2 siRNA oligo Duplex | 933 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308501 | Pre-made Rat Cd22 siRNA oligo Duplex | 308501 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12483 | Pre-made Mouse Cd22/Lyb8/Lyb-8 siRNA oligo Duplex | 12483 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106994739 | Pre-made Cynomolgus/Rhesus macaque CD22 siRNA oligo Duplex | 106994739 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081100 | Pre-made Cat/Feline CD22 siRNA oligo Duplex | 101081100 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476485 | Pre-made Dog/Canine CD22 siRNA oligo Duplex | 476485 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514582 | Pre-made Bovines/Cattle CD22 siRNA oligo Duplex | 514582 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146402 | Pre-made Equine/Horse CD22 siRNA oligo Duplex | 100146402 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD22 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T37539-Ab | Human | Anti-Human CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T37539-Ab | Rat | Anti-Rat CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T37539-Ab | Mouse | Anti-Mouse CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T37539-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T37539-Ab | Cat/Feline | Anti-Cat/Feline CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T37539-Ab | Dog/Canine | Anti-Dog/Canine CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T37539-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T37539-Ab | Equine/Horse | Anti-Equine/Horse CD22 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD22 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T37539-Ag | Human | Human CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T37539-Ag | Rat | Rat CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T37539-Ag | Mouse | Mouse CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T37539-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T37539-Ag | Cat/Feline | Cat/Feline CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T37539-Ag | Dog/Canine | Dog/Canine CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T37539-Ag | Bovines/Cattle | Bovines/Cattle CD22 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T37539-Ag | Equine/Horse | Equine/Horse CD22 VLP (virus-like particle) | HEK293 | Products Developing |
