Explore Cathepsin A/CTSA gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T37154
|
| Target Name |
Cathepsin A/CTSA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5476
|
| Gene ID |
100071127 (Equus caballus), 101085538 (Felis catus), 19025 (Mus musculus), 296370 (Rattus norvegicus) 518169 (Bos taurus), 5476 (Homo sapiens), 611146 (Canis lupus familiaris), 708592 (Macaca mulatta)
|
| Target Alternative Names |
CTSA,Carboxypeptidase C,Carboxypeptidase L,Cathepsin A,Ctsa,GLB2,GSL,Lysosomal protective protein,NGBE,PPCA,PPGB,Ppgb,Protective protein cathepsin A (PPCA),Protective protein for beta-galactosidase
|
| Uniprot Accession |
P16675,Q3MI05,P10619
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Lysosome, Renin-angiotensin system
|
| Gene Ensembl |
ENSECAG00000002350, ENSMUSG00000017760, ENSBTAG00000027337, ENSG00000064601, ENSCAFG00845016332, ENSMMUG00000009960
|
Pre-made viral vector of Cathepsin A/CTSA cDNA Clones/ORF Plasmid
Cathepsin A/CTSA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5476 | Pre-made Human CTSA/GSL/GLB2 siRNA oligo Duplex | 5476 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296370 | Pre-made Rat Ctsa/Ppgb siRNA oligo Duplex | 296370 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19025 | Pre-made Mouse Ctsa/PPCA/Ppgb siRNA oligo Duplex | 19025 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708592 | Pre-made Cynomolgus/Rhesus macaque CTSA/PPGB siRNA oligo Duplex | 708592 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085538 | Pre-made Cat/Feline CTSA siRNA oligo Duplex | 101085538 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611146 | Pre-made Dog/Canine CTSA/PPGB siRNA oligo Duplex | 611146 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo518169 | Pre-made Bovines/Cattle CTSA/PPCA siRNA oligo Duplex | 518169 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071127 | Pre-made Equine/Horse CTSA siRNA oligo Duplex | 100071127 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cathepsin A/CTSA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T37154-Ab | Human | Anti-Human Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T37154-Ab | Rat | Anti-Rat Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T37154-Ab | Mouse | Anti-Mouse Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T37154-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T37154-Ab | Cat/Feline | Anti-Cat/Feline Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T37154-Ab | Dog/Canine | Anti-Dog/Canine Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T37154-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T37154-Ab | Equine/Horse | Anti-Equine/Horse Cathepsin A/CTSA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cathepsin A/CTSA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T37154-Ag | Human | Human Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T37154-Ag | Rat | Rat Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T37154-Ag | Mouse | Mouse Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T37154-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T37154-Ag | Cat/Feline | Cat/Feline Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T37154-Ag | Dog/Canine | Dog/Canine Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T37154-Ag | Bovines/Cattle | Bovines/Cattle Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T37154-Ag | Equine/Horse | Equine/Horse Cathepsin A/CTSA recombinant protein | Mammalian cell | Detail |