Explore GFRAL gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Enables glial cell-derived neurotrophic factor receptor activity and receptor tyrosine kinase binding activity. Involved in glial cell-derived neurotrophic factor receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of protein kinase B signaling. Located in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T37012
|
| Target Name |
GFRAL
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
389400
|
| Gene ID |
100069686 (Equus caballus), 101097066 (Felis catus), 389400 (Homo sapiens), 404194 (Mus musculus)
481851 (Canis lupus familiaris), 501023 (Rattus norvegicus), 531956 (Bos taurus), 714935 (Macaca mulatta)
|
| Target Alternative Names |
GFRAL,Gfral,GRAL,UNQ9356,C6orf144,bA360D14.1,Gral,RGD1565220
|
| Uniprot Accession |
Q6UXV0,Q6SJE0,D3ZB94
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000024885, ENSG00000187871, ENSMUSG00000059383, ENSCAFG00845011491, ENSMMUG00000051331
|
| Target Classification |
|
Pre-made viral vector of GFRAL cDNA Clones/ORF Plasmid
GFRAL siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo389400 | Pre-made Human GFRAL/GRAL/UNQ9356 siRNA oligo Duplex | 389400 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo501023 | Pre-made Rat Gfral/RGD1565220 siRNA oligo Duplex | 501023 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo404194 | Pre-made Mouse Gfral/Gral siRNA oligo Duplex | 404194 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714935 | Pre-made Cynomolgus/Rhesus macaque GFRAL siRNA oligo Duplex | 714935 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097066 | Pre-made Cat/Feline GFRAL siRNA oligo Duplex | 101097066 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481851 | Pre-made Dog/Canine GFRAL siRNA oligo Duplex | 481851 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo531956 | Pre-made Bovines/Cattle GFRAL siRNA oligo Duplex | 531956 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069686 | Pre-made Equine/Horse GFRAL siRNA oligo Duplex | 100069686 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GFRAL antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T37012-Ab | Human | Anti-Human GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T37012-Ab | Rat | Anti-Rat GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T37012-Ab | Mouse | Anti-Mouse GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T37012-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T37012-Ab | Cat/Feline | Anti-Cat/Feline GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T37012-Ab | Dog/Canine | Anti-Dog/Canine GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T37012-Ab | Bovines/Cattle | Anti-Bovines/Cattle GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T37012-Ab | Equine/Horse | Anti-Equine/Horse GFRAL monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
GFRAL VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T37012-Ag | Human | Human GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T37012-Ag | Rat | Rat GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T37012-Ag | Mouse | Mouse GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T37012-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T37012-Ag | Cat/Feline | Cat/Feline GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T37012-Ag | Dog/Canine | Dog/Canine GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T37012-Ag | Bovines/Cattle | Bovines/Cattle GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T37012-Ag | Equine/Horse | Equine/Horse GFRAL VLP (virus-like particle) | HEK293 | Products Developing |
