Explore PAR1/Thrombin Receptor/F2R gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Target ID |
GM-T36483
|
Target Name |
PAR1/Thrombin Receptor/F2R
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2149
|
Gene ID |
100073278 (Equus caballus), 101100861 (Felis catus), 14062 (Mus musculus), 2149 (Homo sapiens) 25439 (Rattus norvegicus), 488942 (Canis lupus familiaris), 526585 (Bos taurus), 707370 (Macaca mulatta)
|
Target Alternative Names |
F2R,F2r,Cf2r,Par1,ThrR,TR,HTR,CF2R,PAR1,PAR-1,TRGPC
|
Uniprot Accession |
P30558,P25116,P26824,A7YY44
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
Rap1 signaling pathway, Calcium signaling pathway, cAMP signaling pathway, Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Pathways in cancer
|
Gene Ensembl |
ENSECAG00000004055, ENSMUSG00000048376, ENSG00000181104, ENSCAFG00845010276, ENSBTAG00000020199, ENSMMUG00000039522
|
Target Classification |
GPCR
|
Pre-made viral vector of PAR1/Thrombin Receptor/F2R cDNA Clones/ORF Plasmid
PAR1/Thrombin Receptor/F2R siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo2149 | Pre-made Human F2R/TR/HTR siRNA oligo Duplex | 2149 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25439 | Pre-made Rat F2r/Par1/TRGPC siRNA oligo Duplex | 25439 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo14062 | Pre-made Mouse F2r/Cf2r/Par1 siRNA oligo Duplex | 14062 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo707370 | Pre-made Cynomolgus/Rhesus macaque F2R siRNA oligo Duplex | 707370 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101100861 | Pre-made Cat/Feline F2R siRNA oligo Duplex | 101100861 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo488942 | Pre-made Dog/Canine F2R siRNA oligo Duplex | 488942 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo526585 | Pre-made Bovines/Cattle F2R/PAR1 siRNA oligo Duplex | 526585 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100073278 | Pre-made Equine/Horse F2R siRNA oligo Duplex | 100073278 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PAR1/Thrombin Receptor/F2R antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T36483-Ab | Human | Anti-Human PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-T36483-Ab | Rat | Anti-Rat PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-T36483-Ab | Mouse | Anti-Mouse PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T36483-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-T36483-Ab | Cat/Feline | Anti-Cat/Feline PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-T36483-Ab | Dog/Canine | Anti-Dog/Canine PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T36483-Ab | Bovines/Cattle | Anti-Bovines/Cattle PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T36483-Ab | Equine/Horse | Anti-Equine/Horse PAR1/Thrombin Receptor/F2R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PAR1/Thrombin Receptor/F2R VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T36483-Ag | Human | Human PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-T36483-Ag | Rat | Rat PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-T36483-Ag | Mouse | Mouse PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-T36483-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-T36483-Ag | Cat/Feline | Cat/Feline PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-T36483-Ag | Dog/Canine | Dog/Canine PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-T36483-Ag | Bovines/Cattle | Bovines/Cattle PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-T36483-Ag | Equine/Horse | Equine/Horse PAR1/Thrombin Receptor/F2R VLP (virus-like particle) | HEK293 | Products Developing |