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Target
sublocation: Transmembrane Protein.
This gene encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2009]
| Target ID |
GM-T36440
|
| Target Name |
AMHR2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
269
|
| Gene ID |
100063905 (Equus caballus), 101085902 (Felis catus), 110542 (Mus musculus), 269 (Homo sapiens) 29530 (Rattus norvegicus), 486506 (Canis lupus familiaris), 514963 (Bos taurus), 702822 (Macaca mulatta)
|
| Target Alternative Names |
AMHR,AMHR2,Amhr2,Anti-Muellerian hormone type II receptor (AMH type II receptor),Anti-Muellerian hormone type-2 receptor,C14,MIS type II receptor (MISRII,MISR2,MISRII,MRII,MRII),Misiir,Misrii,Mrii
|
| Uniprot Accession |
Q8K592,Q16671,Q62893
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
|
| Gene Ensembl |
ENSECAG00000020247, ENSMUSG00000023047, ENSG00000135409, ENSBTAG00000018524, ENSMMUG00000020037
|
| Target Classification |
Pathway
|
Pre-made viral vector of AMHR2 cDNA Clones/ORF Plasmid
AMHR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo269 | Pre-made Human AMHR2/AMHR/MRII siRNA oligo Duplex | 269 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29530 | Pre-made Rat Amhr2/C14/MRII siRNA oligo Duplex | 29530 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110542 | Pre-made Mouse Amhr2/C14/Mrii siRNA oligo Duplex | 110542 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702822 | Pre-made Cynomolgus/Rhesus macaque AMHR2 siRNA oligo Duplex | 702822 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085902 | Pre-made Cat/Feline AMHR2 siRNA oligo Duplex | 101085902 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486506 | Pre-made Dog/Canine AMHR2 siRNA oligo Duplex | 486506 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514963 | Pre-made Bovines/Cattle AMHR2 siRNA oligo Duplex | 514963 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063905 | Pre-made Equine/Horse AMHR2 siRNA oligo Duplex | 100063905 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AMHR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T36440-Ab | Human | Anti-Human AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T36440-Ab | Rat | Anti-Rat AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T36440-Ab | Mouse | Anti-Mouse AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T36440-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T36440-Ab | Cat/Feline | Anti-Cat/Feline AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T36440-Ab | Dog/Canine | Anti-Dog/Canine AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T36440-Ab | Bovines/Cattle | Anti-Bovines/Cattle AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T36440-Ab | Equine/Horse | Anti-Equine/Horse AMHR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
AMHR2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T36440-Ag | Human | Human AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T36440-Ag | Rat | Rat AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T36440-Ag | Mouse | Mouse AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T36440-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T36440-Ag | Cat/Feline | Cat/Feline AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T36440-Ag | Dog/Canine | Dog/Canine AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T36440-Ag | Bovines/Cattle | Bovines/Cattle AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T36440-Ag | Equine/Horse | Equine/Horse AMHR2 VLP (virus-like particle) | HEK293 | Products Developing |