Nectin-4/PVRL4/NECTIN4 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Nectin-4/PVRL4/NECTIN4 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

Target ID GM-T35591
Target Name Nectin-4/PVRL4/NECTIN4
Gene Group ldentifer
(Target Gene ID in Homo species)
81607
Gene ID 100066309 (Equus caballus), 101092485 (Felis catus), 498281 (Rattus norvegicus), 507718 (Bos taurus)
609931 (Canis lupus familiaris), 71740 (Mus musculus), 719843 (Macaca mulatta), 81607 (Homo sapiens)
Target Alternative Names 1200017F15Rik,EDSS1,Ig superfamily receptor LNIR,LNIR,NECTIN4,Nectin cell adhesion molecule 4,Nectin-4,Nectin4,PRR4,PVRL4,Poliovirus receptor-related protein 4,Prr4,Pvrl4,RGD1559826,nectin-4
Uniprot Accession Q5E9Z9,Q8R007,Q96NY8
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, Immuno-oncology Target, INN Index
Disease Breast Cancer, Mucocutaneous lymph node syndrome [Kawasaki]
Disease from KEGG Adherens junction
Gene Ensembl ENSECAG00000016260, ENSBTAG00000017877, ENSCAFG00845029874, ENSMUSG00000006411, ENSMMUG00000064337, ENSG00000143217
Target Classification Checkpoint-Immuno Oncology


Pre-made viral vector of Nectin-4/PVRL4/NECTIN4 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP002312Human NECTIN4/EDSS1/LNIR Lentivirus plasmidNM_03091681607HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP002312Human NECTIN4/EDSS1/LNIR Lentivirus particleNM_03091681607HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


Nectin-4/PVRL4/NECTIN4 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo81607Pre-made Human NECTIN4/LNIR/PRR4 siRNA oligo Duplex81607HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo498281Pre-made Rat Nectin4/Pvrl4/RGD1559826 siRNA oligo Duplex498281RatIn-vitro grade; in-vivo gradeDetail
pGMoligo71740Pre-made Mouse Nectin4/Prr4/Pvrl4 siRNA oligo Duplex71740MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo719843Pre-made Cynomolgus/Rhesus macaque NECTIN4 siRNA oligo Duplex719843Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092485Pre-made Cat/Feline NECTIN4 siRNA oligo Duplex101092485Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo609931Pre-made Dog/Canine NECTIN4/nectin-4 siRNA oligo Duplex609931Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo507718Pre-made Bovines/Cattle NECTIN4/PVRL4 siRNA oligo Duplex507718Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100066309Pre-made Equine/Horse NECTIN4 siRNA oligo Duplex100066309Equine/HorseIn-vitro grade; in-vivo gradeDetail


Nectin-4/PVRL4/NECTIN4 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T35591-AbHumanAnti-Human Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T35591-AbRatAnti-Rat Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T35591-AbMouseAnti-Mouse Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T35591-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T35591-AbCat/FelineAnti-Cat/Feline Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T35591-AbDog/CanineAnti-Dog/Canine Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T35591-AbBovines/CattleAnti-Bovines/Cattle Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T35591-AbEquine/HorseAnti-Equine/Horse Nectin-4/PVRL4/NECTIN4 monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T35591-AgHumanHuman Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T35591-AgRatRat Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T35591-AgMouseMouse Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T35591-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T35591-AgCat/FelineCat/Feline Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T35591-AgDog/CanineDog/Canine Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T35591-AgBovines/CattleBovines/Cattle Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T35591-AgEquine/HorseEquine/Horse Nectin-4/PVRL4/NECTIN4 VLP (virus-like particle)HEK293Products Developing