Explore SCN11A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is highly expressed in nociceptive neurons of dorsal root ganglia and trigeminal ganglia. It mediates brain-derived neurotrophic factor-evoked membrane depolarization and is a major effector of peripheral inflammatory pain hypersensitivity. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy type VII and familial episodic pain syndrome-3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]
| Target ID |
GM-T34123
|
| Target Name |
SCN11A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11280
|
| Gene ID |
100068480 (Equus caballus), 101085312 (Felis catus), 11280 (Homo sapiens), 24046 (Mus musculus)
29701 (Rattus norvegicus), 485593 (Canis lupus familiaris), 535956 (Bos taurus), 695258 (Macaca mulatta)
|
| Target Alternative Names |
FEPS3,HSAN7,NAV1.9,NSS2,NaN,NaT,NaV1.9,PN5,Peripheral nerve sodium channel 5 (PN5),SCN11A,SCN12A,SNS-2,SNS2,Scn11a,Sensory neuron sodium channel 2,Sodium channel protein type 11 subunit alpha,Sodium channel protein type XI subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.9,hNaN
|
| Uniprot Accession |
Q9UI33,Q9R053,O88457
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000016287, ENSG00000168356, ENSMUSG00000034115, ENSCAFG00845030314, ENSBTAG00000017174, ENSMMUG00000019962
|
SCN11A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11280 | Pre-made Human SCN11A/NaN/PN5 siRNA oligo Duplex | 11280 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29701 | Pre-made Rat Scn11a/NaN siRNA oligo Duplex | 29701 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24046 | Pre-made Mouse Scn11a/NaN/NaT siRNA oligo Duplex | 24046 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695258 | Pre-made Cynomolgus/Rhesus macaque SCN11A siRNA oligo Duplex | 695258 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085312 | Pre-made Cat/Feline SCN11A siRNA oligo Duplex | 101085312 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485593 | Pre-made Dog/Canine SCN11A siRNA oligo Duplex | 485593 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535956 | Pre-made Bovines/Cattle SCN11A siRNA oligo Duplex | 535956 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068480 | Pre-made Equine/Horse SCN11A siRNA oligo Duplex | 100068480 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SCN11A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T34123-Ab | Human | Anti-Human SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T34123-Ab | Rat | Anti-Rat SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T34123-Ab | Mouse | Anti-Mouse SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T34123-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T34123-Ab | Cat/Feline | Anti-Cat/Feline SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T34123-Ab | Dog/Canine | Anti-Dog/Canine SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T34123-Ab | Bovines/Cattle | Anti-Bovines/Cattle SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T34123-Ab | Equine/Horse | Anti-Equine/Horse SCN11A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
SCN11A VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T34123-Ag | Human | Human SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T34123-Ag | Rat | Rat SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T34123-Ag | Mouse | Mouse SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T34123-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T34123-Ag | Cat/Feline | Cat/Feline SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T34123-Ag | Dog/Canine | Dog/Canine SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T34123-Ag | Bovines/Cattle | Bovines/Cattle SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T34123-Ag | Equine/Horse | Equine/Horse SCN11A VLP (virus-like particle) | HEK293 | Products Developing |
