Explore M-CSF/CSF1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
| Target ID |
GM-T33990
|
| Target Name |
M-CSF/CSF1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1435
|
| Gene ID |
100146493 (Equus caballus), 101091467 (Felis catus), 12977 (Mus musculus), 1435 (Homo sapiens)
281094 (Bos taurus), 611795 (Canis lupus familiaris), 702532 (Macaca mulatta), 78965 (Rattus norvegicus)
|
| Target Alternative Names |
BAP025,CSF-1,CSF1,Csf1,Csfm,Lanimostim,M-CSF,MCSF,Macrophage colony-stimulating factor 1,Mhdabap25,PG-M-CSF,Proteoglycan macrophage colony-stimulating factor (PG-M-CSF),op
|
| Uniprot Accession |
P07141,P09603,Q8JZQ0
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
cancer, Breast Cancer, ovarian cancer, Lupus Glomerulonephritis, Autosomal Dominant Polycystic Kidney Disease
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, PI3K-Akt signaling pathway, Osteoclast differentiation, Hematopoietic cell lineage, TNF signaling pathway, Alzheimer disease, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000017715, ENSMUSG00000014599, ENSG00000184371, ENSBTAG00000000283, ENSCAFG00845002371, ENSMMUG00000002680
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of M-CSF/CSF1 cDNA Clones/ORF Plasmid
M-CSF/CSF1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1435 | Pre-made Human CSF1/MCSF/CSF-1 siRNA oligo Duplex | 1435 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo78965 | Pre-made Rat Csf1/PG-M-CSF siRNA oligo Duplex | 78965 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12977 | Pre-made Mouse Csf1/op/Csfm siRNA oligo Duplex | 12977 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702532 | Pre-made Cynomolgus/Rhesus macaque CSF1 siRNA oligo Duplex | 702532 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091467 | Pre-made Cat/Feline CSF1 siRNA oligo Duplex | 101091467 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611795 | Pre-made Dog/Canine CSF1 siRNA oligo Duplex | 611795 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281094 | Pre-made Bovines/Cattle CSF1 siRNA oligo Duplex | 281094 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146493 | Pre-made Equine/Horse CSF1 siRNA oligo Duplex | 100146493 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
M-CSF/CSF1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T33990-Ab | Human | Anti-Human M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T33990-Ab | Rat | Anti-Rat M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T33990-Ab | Mouse | Anti-Mouse M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T33990-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T33990-Ab | Cat/Feline | Anti-Cat/Feline M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T33990-Ab | Dog/Canine | Anti-Dog/Canine M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T33990-Ab | Bovines/Cattle | Anti-Bovines/Cattle M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T33990-Ab | Equine/Horse | Anti-Equine/Horse M-CSF/CSF1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
M-CSF/CSF1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T33990-Ag | Human | Human M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T33990-Ag | Rat | Rat M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T33990-Ag | Mouse | Mouse M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T33990-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T33990-Ag | Cat/Feline | Cat/Feline M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T33990-Ag | Dog/Canine | Dog/Canine M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T33990-Ag | Bovines/Cattle | Bovines/Cattle M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T33990-Ag | Equine/Horse | Equine/Horse M-CSF/CSF1 VLP (virus-like particle) | HEK293 | Products Developing |
