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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014]
| Target ID |
GM-T32348
|
| Target Name |
EGR1/EGR-1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1958
|
| Gene ID |
100072574 (Equus caballus), 101088388 (Felis catus), 13653 (Mus musculus), 1958 (Homo sapiens) 24330 (Rattus norvegicus), 407125 (Bos taurus), 481528 (Canis lupus familiaris), 716786 (Macaca mulatta)
|
| Target Alternative Names |
A530045N19Rik,AT225,EGR-1,EGR1,ETR103,Early growth response protein 1,Egr-1,Egr1,G0S30,KROX-24,Krox-1,Krox-24,Krox24,NGF1-A,NGFI-A,NGFIA,Nerve growth factor-induced protein A (NGFI-A),Ngf1,Ngfi,TIS8,Transcription factor ETR103,Transcription factor Zif268,ZIF-268,ZIF268,ZNF225,Zenk,Zfp-6,Zif268,Zinc finger protein 225,Zinc finger protein Krox-24,egr,zif-268
|
| Uniprot Accession |
P08046,P18146,P08154,Q29W20
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
GnRH signaling pathway, Parathyroid hormone synthesis, secretion and action, AGE-RAGE signaling pathway in diabetic complications, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000014338, ENSMUSG00000038418, ENSG00000120738, ENSBTAG00000010069, ENSCAFG00845021860, ENSMMUG00000055069
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of EGR1/EGR-1 cDNA Clones/ORF Plasmid
EGR1/EGR-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1958 | Pre-made Human EGR1/TIS8/AT225 siRNA oligo Duplex | 1958 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24330 | Pre-made Rat Egr1/Ngf1/Ngfi siRNA oligo Duplex | 24330 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13653 | Pre-made Mouse Egr1/egr/TIS8 siRNA oligo Duplex | 13653 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716786 | Pre-made Cynomolgus/Rhesus macaque EGR1 siRNA oligo Duplex | 716786 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088388 | Pre-made Cat/Feline EGR1 siRNA oligo Duplex | 101088388 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481528 | Pre-made Dog/Canine EGR1 siRNA oligo Duplex | 481528 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407125 | Pre-made Bovines/Cattle EGR1 siRNA oligo Duplex | 407125 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072574 | Pre-made Equine/Horse EGR1 siRNA oligo Duplex | 100072574 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EGR1/EGR-1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T32348-Ab | Human | Anti-Human EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T32348-Ab | Rat | Anti-Rat EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T32348-Ab | Mouse | Anti-Mouse EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T32348-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T32348-Ab | Cat/Feline | Anti-Cat/Feline EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T32348-Ab | Dog/Canine | Anti-Dog/Canine EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T32348-Ab | Bovines/Cattle | Anti-Bovines/Cattle EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T32348-Ab | Equine/Horse | Anti-Equine/Horse EGR1/EGR-1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
EGR1/EGR-1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T32348-Ag | Human | Human EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T32348-Ag | Rat | Rat EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T32348-Ag | Mouse | Mouse EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T32348-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T32348-Ag | Cat/Feline | Cat/Feline EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T32348-Ag | Dog/Canine | Dog/Canine EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T32348-Ag | Bovines/Cattle | Bovines/Cattle EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T32348-Ag | Equine/Horse | Equine/Horse EGR1/EGR-1 recombinant protein | Mammalian cell | Detail |