Explore CALCRL/CGRPR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Enables adrenomedullin binding activity; adrenomedullin receptor activity; and calcitonin gene-related peptide receptor activity. Involved in several processes, including G protein-coupled receptor signaling pathway; cellular response to sucrose stimulus; and receptor internalization. Located in endoplasmic reticulum; endosome; and lysosome. Part of CGRP receptor complex and adrenomedullin receptor complex. Colocalizes with plasma membrane. Implicated in hereditary lymphedema. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-T32262
|
| Target Name |
CALCRL/CGRPR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10203
|
| Gene ID |
100054281 (Equus caballus), 101086333 (Felis catus), 10203 (Homo sapiens), 25029 (Rattus norvegicus)
488438 (Canis lupus familiaris), 527140 (Bos taurus), 54598 (Mus musculus), 708187 (Macaca mulatta)
|
| Target Alternative Names |
CALCRL,CGRP type 1 receptor,CGRPR,CLR,CRLR,Calcitonin gene-related peptide type 1 receptor,Calcitonin receptor-like receptor (CRLR),Calcrl,Crlr,LMPHM8,RATCRLR,RNCLR
|
| Uniprot Accession |
Q16602,Q63118,A6QP74,Q9R1W5
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction
|
| Gene Ensembl |
ENSECAG00000012990, ENSG00000064989, ENSCAFG00845018739, ENSBTAG00000008483, ENSMUSG00000059588, ENSMMUG00000009447
|
| Target Classification |
GPCR
|
Pre-made viral vector of CALCRL/CGRPR cDNA Clones/ORF Plasmid
CALCRL/CGRPR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10203 | Pre-made Human CALCRL/CRLR/CGRPR siRNA oligo Duplex | 10203 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25029 | Pre-made Rat Calcrl/CLR/Crlr siRNA oligo Duplex | 25029 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo54598 | Pre-made Mouse Calcrl/CRLR siRNA oligo Duplex | 54598 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708187 | Pre-made Cynomolgus/Rhesus macaque CALCRL siRNA oligo Duplex | 708187 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086333 | Pre-made Cat/Feline CALCRL siRNA oligo Duplex | 101086333 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488438 | Pre-made Dog/Canine CALCRL siRNA oligo Duplex | 488438 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo527140 | Pre-made Bovines/Cattle CALCRL siRNA oligo Duplex | 527140 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054281 | Pre-made Equine/Horse CALCRL siRNA oligo Duplex | 100054281 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CALCRL/CGRPR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T32262-Ab | Human | Anti-Human CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T32262-Ab | Rat | Anti-Rat CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T32262-Ab | Mouse | Anti-Mouse CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T32262-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T32262-Ab | Cat/Feline | Anti-Cat/Feline CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T32262-Ab | Dog/Canine | Anti-Dog/Canine CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T32262-Ab | Bovines/Cattle | Anti-Bovines/Cattle CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T32262-Ab | Equine/Horse | Anti-Equine/Horse CALCRL/CGRPR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CALCRL/CGRPR VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T32262-Ag | Human | Human CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T32262-Ag | Rat | Rat CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T32262-Ag | Mouse | Mouse CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T32262-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T32262-Ag | Cat/Feline | Cat/Feline CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T32262-Ag | Dog/Canine | Dog/Canine CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T32262-Ag | Bovines/Cattle | Bovines/Cattle CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T32262-Ag | Equine/Horse | Equine/Horse CALCRL/CGRPR VLP (virus-like particle) | HEK293 | Products Developing |
