Explore 5HT2A/HTR2A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
| Target ID |
GM-T32060
|
| Target Name |
5HT2A/HTR2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3356
|
| Gene ID |
100009685 (Equus caballus), 101081108 (Felis catus), 15558 (Mus musculus), 29595 (Rattus norvegicus)
3356 (Homo sapiens), 403882 (Canis lupus familiaris), 407230 (Bos taurus), 613032 (Macaca mulatta)
|
| Target Alternative Names |
HTR2A,Htr2a,Htr2,Htr-2,5-HT-2,5-HT-2A,E030013E04,5Ht-2,5-HT2A,HTR2,5-HTR2A,5HT2A,5HTR2A
|
| Uniprot Accession |
P35363,P14842,P28223,O46635,Q75Z89,P50128
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Schizophrenia
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Gap junction, Serotonergic synapse, Inflammatory mediator regulation of TRP channels
|
| Gene Ensembl |
ENSECAG00000024282, ENSMUSG00000034997, ENSG00000102468, ENSCAFG00845007028, ENSBTAG00000013498, ENSMMUG00000004210
|
| Target Classification |
GPCR
|
Pre-made viral vector of 5HT2A/HTR2A cDNA Clones/ORF Plasmid
5HT2A/HTR2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3356 | Pre-made Human HTR2A/HTR2/5-HT2A siRNA oligo Duplex | 3356 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29595 | Pre-made Rat Htr2a/5Ht-2/5-HT2A siRNA oligo Duplex | 29595 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15558 | Pre-made Mouse Htr2a/Htr2/Htr-2 siRNA oligo Duplex | 15558 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613032 | Pre-made Cynomolgus/Rhesus macaque HTR2A siRNA oligo Duplex | 613032 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101081108 | Pre-made Cat/Feline HTR2A siRNA oligo Duplex | 101081108 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403882 | Pre-made Dog/Canine HTR2A/5-HT-2/5-HT-2A siRNA oligo Duplex | 403882 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407230 | Pre-made Bovines/Cattle HTR2A/5HT2A/5HTR2A siRNA oligo Duplex | 407230 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009685 | Pre-made Equine/Horse HTR2A siRNA oligo Duplex | 100009685 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
5HT2A/HTR2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T32060-Ab | Human | Anti-Human 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T32060-Ab | Rat | Anti-Rat 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T32060-Ab | Mouse | Anti-Mouse 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T32060-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T32060-Ab | Cat/Feline | Anti-Cat/Feline 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T32060-Ab | Dog/Canine | Anti-Dog/Canine 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T32060-Ab | Bovines/Cattle | Anti-Bovines/Cattle 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T32060-Ab | Equine/Horse | Anti-Equine/Horse 5HT2A/HTR2A monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
5HT2A/HTR2A VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T32060-Ag | Human | Human 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T32060-Ag | Rat | Rat 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T32060-Ag | Mouse | Mouse 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T32060-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T32060-Ag | Cat/Feline | Cat/Feline 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T32060-Ag | Dog/Canine | Dog/Canine 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T32060-Ag | Bovines/Cattle | Bovines/Cattle 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T32060-Ag | Equine/Horse | Equine/Horse 5HT2A/HTR2A VLP (virus-like particle) | HEK293 | Products Developing |
