SPHK2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SPHK2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

Target ID	GM-T31989
Target Name	SPHK2
Gene Group ldentifer （Target Gene ID in Homo species)	56848
Gene ID	100054066 (Equus caballus), 101081345 (Felis catus), 308589 (Rattus norvegicus), 484401 (Canis lupus familiaris) 533103 (Bos taurus), 56632 (Mus musculus), 56848 (Homo sapiens), 718088 (Macaca mulatta)
Target Alternative Names	SK 2,SK-2,SPHK2,SPK 2,SPK-2,Sk2,Sphingosine kinase 2,Sphk2,Spk2
Uniprot Accession	Q9JIA7,Q9NRA0
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease from KEGG	Metabolic pathways, Calcium signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Tuberculosis, Sphingolipid metabolism
Gene Ensembl	ENSECAG00000007474, ENSCAFG00845000947, ENSBTAG00000009872, ENSMUSG00000057342, ENSG00000063176, ENSMMUG00000022159

Pre-made viral vector of SPHK2 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP005396	Human SPHK2/SK 2/SK-2 Lentivirus plasmid	NM_020126.4	56848	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAAV000300	Human SPHK2/SK 2/SK-2 Adeno-associate virus(AAV) plasmid	NM_020126	56848	Human	Adeno-associate virus(AAV) plasmid	GFP	3xflag (C-Terminal)	CTNT	Detail
vGMLP005396	Human SPHK2/SK 2/SK-2 Lentivirus particle	NM_020126.4	56848	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAAV000300	Human SPHK2/SK 2/SK-2 Adeno-associate virus(AAV) particle	NM_020126	56848	Human	Adeno-associate virus(AAV) particle	GFP	3xflag (C-Terminal)	CTNT	Detail
pGMLPm004048	Mouse Sphk2/C76851 Lentivirus plasmid	NM_020011	56632	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm004048	Mouse Sphk2/C76851 Lentivirus particle	NM_020011	56632	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

SPHK2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo56848	Pre-made Human SPHK2/SK 2/SK-2 siRNA oligo Duplex	56848	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo308589	Pre-made Rat Sphk2 siRNA oligo Duplex	308589	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo56632	Pre-made Mouse Sphk2/Sk2/Spk2 siRNA oligo Duplex	56632	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo718088	Pre-made Cynomolgus/Rhesus macaque SPHK2 siRNA oligo Duplex	718088	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101081345	Pre-made Cat/Feline SPHK2 siRNA oligo Duplex	101081345	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo484401	Pre-made Dog/Canine SPHK2 siRNA oligo Duplex	484401	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo533103	Pre-made Bovines/Cattle SPHK2 siRNA oligo Duplex	533103	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100054066	Pre-made Equine/Horse SPHK2 siRNA oligo Duplex	100054066	Equine/Horse	In-vitro grade; in-vivo grade	Detail

SPHK2 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T31989-Ab	Human	Anti-Human SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T31989-Ab	Rat	Anti-Rat SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T31989-Ab	Mouse	Anti-Mouse SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T31989-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T31989-Ab	Cat/Feline	Anti-Cat/Feline SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T31989-Ab	Dog/Canine	Anti-Dog/Canine SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T31989-Ab	Bovines/Cattle	Anti-Bovines/Cattle SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T31989-Ab	Equine/Horse	Anti-Equine/Horse SPHK2 monoclonal antibody	mab	Therapeutics Target antibody	Detail

SPHK2 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T31989-Ag	Human	Human SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T31989-Ag	Rat	Rat SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T31989-Ag	Mouse	Mouse SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T31989-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T31989-Ag	Cat/Feline	Cat/Feline SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T31989-Ag	Dog/Canine	Dog/Canine SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T31989-Ag	Bovines/Cattle	Bovines/Cattle SPHK2 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T31989-Ag	Equine/Horse	Equine/Horse SPHK2 recombinant protein	Mammalian cell	Detail