Explore ENPEP/CD249 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19. [provided by RefSeq, Apr 2020]
| Target ID |
GM-T31956
|
| Target Name |
ENPEP/CD249
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2028
|
| Gene ID |
100072821 (Equus caballus), 101082308 (Felis catus), 13809 (Mus musculus), 2028 (Homo sapiens)
478517 (Canis lupus familiaris), 504350 (Bos taurus), 64017 (Rattus norvegicus), 699615 (Macaca mulatta)
|
| Target Alternative Names |
6030431M22Rik,APA,Aminopeptidase A (AP-A),Bp-1/6C3,CD249,Differentiation antigen gp160,EAP,ENPEP,Enpep,Glutamyl aminopeptidase,Ly-51,Ly51,gp160
|
| Uniprot Accession |
P16406,Q07075,Q32LQ0,P50123
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Renin-angiotensin system
|
| Gene Ensembl |
ENSECAG00000009107, ENSMUSG00000028024, ENSG00000138792, ENSCAFG00845015843, ENSBTAG00000008332, ENSMMUG00000005517
|
Pre-made viral vector of ENPEP/CD249 cDNA Clones/ORF Plasmid
ENPEP/CD249 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2028 | Pre-made Human ENPEP/APA/CD249 siRNA oligo Duplex | 2028 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64017 | Pre-made Rat Enpep siRNA oligo Duplex | 64017 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13809 | Pre-made Mouse Enpep/APA/Ly51 siRNA oligo Duplex | 13809 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699615 | Pre-made Cynomolgus/Rhesus macaque ENPEP siRNA oligo Duplex | 699615 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082308 | Pre-made Cat/Feline ENPEP siRNA oligo Duplex | 101082308 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo478517 | Pre-made Dog/Canine ENPEP siRNA oligo Duplex | 478517 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504350 | Pre-made Bovines/Cattle ENPEP siRNA oligo Duplex | 504350 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072821 | Pre-made Equine/Horse ENPEP siRNA oligo Duplex | 100072821 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ENPEP/CD249 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31956-Ab | Human | Anti-Human ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31956-Ab | Rat | Anti-Rat ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31956-Ab | Mouse | Anti-Mouse ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31956-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31956-Ab | Cat/Feline | Anti-Cat/Feline ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31956-Ab | Dog/Canine | Anti-Dog/Canine ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31956-Ab | Bovines/Cattle | Anti-Bovines/Cattle ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31956-Ab | Equine/Horse | Anti-Equine/Horse ENPEP/CD249 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ENPEP/CD249 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31956-Ag | Human | Human ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T31956-Ag | Rat | Rat ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T31956-Ag | Mouse | Mouse ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T31956-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T31956-Ag | Cat/Feline | Cat/Feline ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T31956-Ag | Dog/Canine | Dog/Canine ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T31956-Ag | Bovines/Cattle | Bovines/Cattle ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T31956-Ag | Equine/Horse | Equine/Horse ENPEP/CD249 VLP (virus-like particle) | HEK293 | Products Developing |
