Explore Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]
Target ID |
GM-T31818
|
Target Name |
Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3672
|
Gene ID |
100063434 (Equus caballus), 101089743 (Felis catus), 109700 (Mus musculus), 25118 (Rattus norvegicus) 3672 (Homo sapiens), 489210 (Canis lupus familiaris), 535951 (Bos taurus), 703456 (Macaca mulatta)
|
Target Alternative Names |
ITGA1,Itga1,Vla1,CD49A,E130012M19Rik,VLA1,CD49a
|
Uniprot Accession |
Q3V3R4,P18614,P56199
|
Uniprot Entry Name |
|
Protein Sub-location |
Transmembrane Protein
|
Category |
Therapeutics Target
|
Disease |
cancer
|
Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Human papillomavirus infection, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
Gene Ensembl |
ENSECAG00000017386, ENSMUSG00000042284, ENSG00000213949, ENSCAFG00845000521, ENSBTAG00000016525, ENSMMUG00000001753
|
Target Classification |
Tumor-associated antigen (TAA)
|
Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo3672 | Pre-made Human ITGA1/VLA1/CD49a siRNA oligo Duplex | 3672 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25118 | Pre-made Rat Itga1 siRNA oligo Duplex | 25118 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo109700 | Pre-made Mouse Itga1/Vla1/CD49A siRNA oligo Duplex | 109700 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo703456 | Pre-made Cynomolgus/Rhesus macaque ITGA1 siRNA oligo Duplex | 703456 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101089743 | Pre-made Cat/Feline ITGA1 siRNA oligo Duplex | 101089743 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo489210 | Pre-made Dog/Canine ITGA1 siRNA oligo Duplex | 489210 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo535951 | Pre-made Bovines/Cattle ITGA1 siRNA oligo Duplex | 535951 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100063434 | Pre-made Equine/Horse ITGA1 siRNA oligo Duplex | 100063434 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T31818-Ab | Human | Anti-Human Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-rg-T31818-Ab | Rat | Anti-Rat Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-mg-T31818-Ab | Mouse | Anti-Mouse Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cynog-T31818-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-felg-T31818-Ab | Cat/Feline | Anti-Cat/Feline Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-cang-T31818-Ab | Dog/Canine | Anti-Dog/Canine Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-bovg-T31818-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GM-Tg-equg-T31818-Ab | Equine/Horse | Anti-Equine/Horse Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle)
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T31818-Ag | Human | Human Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-rg-T31818-Ag | Rat | Rat Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-mg-T31818-Ag | Mouse | Mouse Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cynog-T31818-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-felg-T31818-Ag | Cat/Feline | Cat/Feline Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-cang-T31818-Ag | Dog/Canine | Dog/Canine Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-bovg-T31818-Ag | Bovines/Cattle | Bovines/Cattle Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |
GM-Tg-equg-T31818-Ag | Equine/Horse | Equine/Horse Integrin alpha 1/Integrin alpha-1/ITGA1/CD49a/VLA-1 VLP (virus-like particle) | HEK293 | Products Developing |