Explore MCT4/SLC16A3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008]
| Target ID |
GM-T31788
|
| Target Name |
MCT4/SLC16A3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9123
|
| Gene ID |
100056191 (Equus caballus), 101091669 (Felis catus), 483379 (Canis lupus familiaris), 510085 (Bos taurus)
715842 (Macaca mulatta), 80878 (Rattus norvegicus), 80879 (Mus musculus), 9123 (Homo sapiens)
|
| Target Alternative Names |
MCT 3,MCT 4,MCT-3,MCT-4,MCT3,MCT4,Mct3,Mct4,Monocarboxylate transporter 4,SLC16A3,Slc16a3,Solute carrier family 16 member 3
|
| Uniprot Accession |
O35910,P57787,O15427
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Central carbon metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000009524, ENSCAFG00845007246, ENSBTAG00000017461, ENSMMUG00000010121, ENSMUSG00000025161, ENSG00000141526
|
Pre-made viral vector of MCT4/SLC16A3 cDNA Clones/ORF Plasmid
MCT4/SLC16A3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9123 | Pre-made Human SLC16A3/MCT3/MCT4 siRNA oligo Duplex | 9123 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo80878 | Pre-made Rat Slc16a3/MCT4/Mct3 siRNA oligo Duplex | 80878 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo80879 | Pre-made Mouse Slc16a3/Mct3/Mct4 siRNA oligo Duplex | 80879 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715842 | Pre-made Cynomolgus/Rhesus macaque SLC16A3 siRNA oligo Duplex | 715842 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091669 | Pre-made Cat/Feline SLC16A3 siRNA oligo Duplex | 101091669 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483379 | Pre-made Dog/Canine SLC16A3 siRNA oligo Duplex | 483379 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510085 | Pre-made Bovines/Cattle SLC16A3/MCT4 siRNA oligo Duplex | 510085 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056191 | Pre-made Equine/Horse SLC16A3/MCT4 siRNA oligo Duplex | 100056191 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MCT4/SLC16A3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31788-Ab | Human | Anti-Human MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31788-Ab | Rat | Anti-Rat MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31788-Ab | Mouse | Anti-Mouse MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31788-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31788-Ab | Cat/Feline | Anti-Cat/Feline MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31788-Ab | Dog/Canine | Anti-Dog/Canine MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31788-Ab | Bovines/Cattle | Anti-Bovines/Cattle MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31788-Ab | Equine/Horse | Anti-Equine/Horse MCT4/SLC16A3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MCT4/SLC16A3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31788-Ag | Human | Human MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T31788-Ag | Rat | Rat MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T31788-Ag | Mouse | Mouse MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T31788-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T31788-Ag | Cat/Feline | Cat/Feline MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T31788-Ag | Dog/Canine | Dog/Canine MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T31788-Ag | Bovines/Cattle | Bovines/Cattle MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T31788-Ag | Equine/Horse | Equine/Horse MCT4/SLC16A3 VLP (virus-like particle) | HEK293 | Products Developing |
