Explore EAAT3/SLC1A1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. [provided by RefSeq, Mar 2010]
| Target ID |
GM-T31721
|
| Target Name |
EAAT3/SLC1A1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6505
|
| Gene ID |
100059120 (Equus caballus), 101099844 (Felis catus), 20510 (Mus musculus), 25550 (Rattus norvegicus)
282353 (Bos taurus), 403751 (Canis lupus familiaris), 6505 (Homo sapiens), 694947 (Macaca mulatta)
|
| Target Alternative Names |
D130048G10Rik,DCBXA,EAAC1,EAAC2,EAAT3,Eaac1,Eaat3,Excitatory amino acid transporter 3,Excitatory amino-acid carrier 1,MEAAC1,Neuronal and epithelial glutamate transporter,REAAC1,SCZD18,SLC1A1,Slc1a1,Sodium-dependent glutamate/aspartate transporter 3,Solute carrier family 1 member 1,hEAAC1
|
| Uniprot Accession |
P51906,P51907,Q95135,P43005
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Glutamatergic synapse, Protein digestion and absorption
|
| Gene Ensembl |
ENSECAG00000010935, ENSMUSG00000024935, ENSBTAG00000019125, ENSCAFG00845002818, ENSG00000106688, ENSMMUG00000000135
|
Pre-made viral vector of EAAT3/SLC1A1 cDNA Clones/ORF Plasmid
EAAT3/SLC1A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6505 | Pre-made Human SLC1A1/DCBXA/EAAC1 siRNA oligo Duplex | 6505 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25550 | Pre-made Rat Slc1a1/Eaac1/Eaat3 siRNA oligo Duplex | 25550 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20510 | Pre-made Mouse Slc1a1/EAAC1/EAAC2 siRNA oligo Duplex | 20510 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694947 | Pre-made Cynomolgus/Rhesus macaque SLC1A1 siRNA oligo Duplex | 694947 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099844 | Pre-made Cat/Feline SLC1A1 siRNA oligo Duplex | 101099844 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403751 | Pre-made Dog/Canine SLC1A1/EAAC1 siRNA oligo Duplex | 403751 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282353 | Pre-made Bovines/Cattle SLC1A1 siRNA oligo Duplex | 282353 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059120 | Pre-made Equine/Horse SLC1A1 siRNA oligo Duplex | 100059120 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EAAT3/SLC1A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31721-Ab | Human | Anti-Human EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31721-Ab | Rat | Anti-Rat EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31721-Ab | Mouse | Anti-Mouse EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31721-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31721-Ab | Cat/Feline | Anti-Cat/Feline EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31721-Ab | Dog/Canine | Anti-Dog/Canine EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31721-Ab | Bovines/Cattle | Anti-Bovines/Cattle EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31721-Ab | Equine/Horse | Anti-Equine/Horse EAAT3/SLC1A1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EAAT3/SLC1A1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31721-Ag | Human | Human EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T31721-Ag | Rat | Rat EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T31721-Ag | Mouse | Mouse EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T31721-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T31721-Ag | Cat/Feline | Cat/Feline EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T31721-Ag | Dog/Canine | Dog/Canine EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T31721-Ag | Bovines/Cattle | Bovines/Cattle EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T31721-Ag | Equine/Horse | Equine/Horse EAAT3/SLC1A1 VLP (virus-like particle) | HEK293 | Products Developing |
