Explore ST14 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T31543
|
| Target Name |
ST14
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6768
|
| Gene ID |
100072676 (Equus caballus), 101095767 (Felis catus), 114093 (Rattus norvegicus), 19143 (Mus musculus)
489278 (Canis lupus familiaris), 6768 (Homo sapiens), 718848 (Macaca mulatta), 767617 (Bos taurus)
|
| Target Alternative Names |
ARCI11,CAP3,Epithin,HAI,MT-SP1,MTSP1,Matriptase,Membrane-type serine protease 1 (MT-SP1),PRSS14,Prostamin,Prss14,SNC19,ST14,Serine protease 14,Serine protease TADG-15,St14,Suppressor of tumorigenicity 14 protein,TADG15,TMPRSS14,Tmprss14,Tumor-associated differentially-expressed gene 15 protein,mCAP3,matriptase
|
| Uniprot Accession |
P56677,Q9Y5Y6,Q0IIH7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Ovary Cancer
|
| Gene Ensembl |
ENSECAG00000006391, ENSMUSG00000031995, ENSCAFG00845006491, ENSG00000149418, ENSMMUG00000018034, ENSBTAG00000019712
|
Pre-made viral vector of ST14 cDNA Clones/ORF Plasmid
ST14 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6768 | Pre-made Human ST14/HAI/CAP3 siRNA oligo Duplex | 6768 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114093 | Pre-made Rat St14/MT-SP1 siRNA oligo Duplex | 114093 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19143 | Pre-made Mouse St14/mCAP3/MT-SP1 siRNA oligo Duplex | 19143 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo718848 | Pre-made Cynomolgus/Rhesus macaque ST14 siRNA oligo Duplex | 718848 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095767 | Pre-made Cat/Feline ST14 siRNA oligo Duplex | 101095767 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489278 | Pre-made Dog/Canine ST14 siRNA oligo Duplex | 489278 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767617 | Pre-made Bovines/Cattle ST14 siRNA oligo Duplex | 767617 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072676 | Pre-made Equine/Horse ST14 siRNA oligo Duplex | 100072676 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ST14 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31543-Ab | Human | Anti-Human ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31543-Ab | Rat | Anti-Rat ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31543-Ab | Mouse | Anti-Mouse ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31543-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31543-Ab | Cat/Feline | Anti-Cat/Feline ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31543-Ab | Dog/Canine | Anti-Dog/Canine ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31543-Ab | Bovines/Cattle | Anti-Bovines/Cattle ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31543-Ab | Equine/Horse | Anti-Equine/Horse ST14 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ST14 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31543-Ag | Human | Human ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T31543-Ag | Rat | Rat ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T31543-Ag | Mouse | Mouse ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T31543-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T31543-Ag | Cat/Feline | Cat/Feline ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T31543-Ag | Dog/Canine | Dog/Canine ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T31543-Ag | Bovines/Cattle | Bovines/Cattle ST14 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T31543-Ag | Equine/Horse | Equine/Horse ST14 VLP (virus-like particle) | HEK293 | Products Developing |
