Explore GAA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
| Target ID |
GM-T31514
|
| Target Name |
GAA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2548
|
| Gene ID |
100056675 (Equus caballus), 101086359 (Felis catus), 14387 (Mus musculus), 2548 (Homo sapiens)
280798 (Bos taurus), 367562 (Rattus norvegicus), 483352 (Canis lupus familiaris), 712054 (Macaca mulatta)
|
| Target Alternative Names |
Acid maltase,Aglucosidase alfa,E430018M07Rik,GAA,Gaa,LYAG,Lysosomal alpha-glucosidase
|
| Uniprot Accession |
P70699,P10253,Q9MYM4,Q6P7A9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Lysosome
|
| Gene Ensembl |
ENSECAG00000015401, ENSMUSG00000025579, ENSG00000171298, ENSBTAG00000016021, ENSCAFG00845013429, ENSMMUG00000009589
|
Pre-made viral vector of GAA cDNA Clones/ORF Plasmid
GAA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2548 | Pre-made Human GAA/LYAG siRNA oligo Duplex | 2548 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo367562 | Pre-made Rat Gaa siRNA oligo Duplex | 367562 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14387 | Pre-made Mouse Gaa/E430018M07Rik siRNA oligo Duplex | 14387 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712054 | Pre-made Cynomolgus/Rhesus macaque GAA siRNA oligo Duplex | 712054 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086359 | Pre-made Cat/Feline GAA siRNA oligo Duplex | 101086359 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483352 | Pre-made Dog/Canine GAA siRNA oligo Duplex | 483352 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280798 | Pre-made Bovines/Cattle GAA siRNA oligo Duplex | 280798 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056675 | Pre-made Equine/Horse GAA siRNA oligo Duplex | 100056675 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GAA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T31514-Ab | Human | Anti-Human GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T31514-Ab | Rat | Anti-Rat GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T31514-Ab | Mouse | Anti-Mouse GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T31514-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T31514-Ab | Cat/Feline | Anti-Cat/Feline GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T31514-Ab | Dog/Canine | Anti-Dog/Canine GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T31514-Ab | Bovines/Cattle | Anti-Bovines/Cattle GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T31514-Ab | Equine/Horse | Anti-Equine/Horse GAA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GAA VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T31514-Ag | Human | Human GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T31514-Ag | Rat | Rat GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T31514-Ag | Mouse | Mouse GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T31514-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T31514-Ag | Cat/Feline | Cat/Feline GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T31514-Ag | Dog/Canine | Dog/Canine GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T31514-Ag | Bovines/Cattle | Bovines/Cattle GAA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T31514-Ag | Equine/Horse | Equine/Horse GAA VLP (virus-like particle) | HEK293 | Products Developing |
