Explore ORAI1/CRACM gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]
| Target ID |
GM-T30790
|
| Target Name |
ORAI1/CRACM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
84876
|
| Gene ID |
101096922 (Felis catus), 109305 (Mus musculus), 304496 (Rattus norvegicus), 486261 (Canis lupus familiaris)
700190 (Macaca mulatta), 84876 (Homo sapiens)
|
| Target Alternative Names |
CRACM,CRACM1,Calcium release-activated calcium channel protein 1,D730049H07Rik,IMD9,ORAI1,ORAT1,Orai1,Protein orai-1,RGD1311873,TAM2,TMEM142A,Tmem142a,Transmembrane protein 142A,orai-1
|
| Uniprot Accession |
Q8BWG9,Q5M848,Q96D31
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Platelet activation, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome
|
| Gene Ensembl |
ENSMUSG00000049686, ENSG00000276045
|
Pre-made viral vector of ORAI1/CRACM cDNA Clones/ORF Plasmid
ORAI1/CRACM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84876 | Pre-made Human ORAI1/IMD9/TAM2 siRNA oligo Duplex | 84876 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo304496 | Pre-made Rat Orai1/RGD1311873 siRNA oligo Duplex | 304496 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109305 | Pre-made Mouse Orai1/orai-1/Tmem142a siRNA oligo Duplex | 109305 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700190 | Pre-made Cynomolgus/Rhesus macaque ORAI1 siRNA oligo Duplex | 700190 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096922 | Pre-made Cat/Feline ORAI1 siRNA oligo Duplex | 101096922 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486261 | Pre-made Dog/Canine ORAI1 siRNA oligo Duplex | 486261 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
ORAI1/CRACM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T30790-Ab | Human | Anti-Human ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T30790-Ab | Rat | Anti-Rat ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T30790-Ab | Mouse | Anti-Mouse ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T30790-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T30790-Ab | Cat/Feline | Anti-Cat/Feline ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T30790-Ab | Dog/Canine | Anti-Dog/Canine ORAI1/CRACM monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ORAI1/CRACM VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T30790-Ag | Human | Human ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T30790-Ag | Rat | Rat ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T30790-Ag | Mouse | Mouse ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T30790-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T30790-Ag | Cat/Feline | Cat/Feline ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T30790-Ag | Dog/Canine | Dog/Canine ORAI1/CRACM VLP (virus-like particle) | HEK293 | Products Developing |
