Explore IFNGR2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T30284
|
| Target Name |
IFNGR2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3460
|
| Gene ID |
100063333 (Equus caballus), 101092286 (Felis catus), 15980 (Mus musculus), 3460 (Homo sapiens)
360697 (Rattus norvegicus), 487739 (Canis lupus familiaris), 514889 (Bos taurus), 699489 (Macaca mulatta)
|
| Target Alternative Names |
IFNGR2,Ifngr2,Ifgt,Ifgr2,AF-1,IFGR2,IMD28,IFNGT1
|
| Uniprot Accession |
P38484
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Osteoclast differentiation, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, Leishmaniasis, Chagas disease, Toxoplasmosis, Tuberculosis, Influenza A, Pathways in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Inflammatory bowel disease
|
| Gene Ensembl |
ENSECAG00000014660, ENSMUSG00000022965, ENSG00000159128, ENSCAFG00845026979, ENSBTAG00000012899, ENSMMUG00000005508
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
IFNGR2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3460 | Pre-made Human IFNGR2/AF-1/IFGR2 siRNA oligo Duplex | 3460 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360697 | Pre-made Rat Ifngr2 siRNA oligo Duplex | 360697 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15980 | Pre-made Mouse Ifngr2/Ifgt/Ifgr2 siRNA oligo Duplex | 15980 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699489 | Pre-made Cynomolgus/Rhesus macaque IFNGR2 siRNA oligo Duplex | 699489 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092286 | Pre-made Cat/Feline IFNGR2 siRNA oligo Duplex | 101092286 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487739 | Pre-made Dog/Canine IFNGR2 siRNA oligo Duplex | 487739 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514889 | Pre-made Bovines/Cattle IFNGR2 siRNA oligo Duplex | 514889 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063333 | Pre-made Equine/Horse IFNGR2 siRNA oligo Duplex | 100063333 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IFNGR2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T30284-Ab | Human | Anti-Human IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T30284-Ab | Rat | Anti-Rat IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T30284-Ab | Mouse | Anti-Mouse IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T30284-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T30284-Ab | Cat/Feline | Anti-Cat/Feline IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T30284-Ab | Dog/Canine | Anti-Dog/Canine IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T30284-Ab | Bovines/Cattle | Anti-Bovines/Cattle IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T30284-Ab | Equine/Horse | Anti-Equine/Horse IFNGR2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IFNGR2 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T30284-Ag | Human | Human IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T30284-Ag | Rat | Rat IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T30284-Ag | Mouse | Mouse IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T30284-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T30284-Ag | Cat/Feline | Cat/Feline IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T30284-Ag | Dog/Canine | Dog/Canine IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T30284-Ag | Bovines/Cattle | Bovines/Cattle IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T30284-Ag | Equine/Horse | Equine/Horse IFNGR2 VLP (virus-like particle) | HEK293 | Products Developing |
