Explore VEGFB gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]
| Target ID |
GM-T30040
|
| Target Name |
VEGFB
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
7423
|
| Gene ID |
100055238 (Equus caballus), 101092465 (Felis catus), 22340 (Mus musculus), 282121 (Bos taurus)
476036 (Canis lupus familiaris), 722115 (Macaca mulatta), 7423 (Homo sapiens), 89811 (Rattus norvegicus)
|
| Target Alternative Names |
VEGF-B,VEGF-related factor (VRF),VEGFB,VEGFL,VRF,Vascular endothelial growth factor B,Vegfb,Vrf
|
| Uniprot Accession |
P49766,Q9XS49,P49765,O35485
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Relaxin signaling pathway, AGE-RAGE signaling pathway in diabetic complications, Pathways in cancer
|
| Gene Ensembl |
ENSMUSG00000024962, ENSMMUG00000012944, ENSG00000173511
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of VEGFB cDNA Clones/ORF Plasmid
VEGFB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7423 | Pre-made Human VEGFB/VRF/VEGFL siRNA oligo Duplex | 7423 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo89811 | Pre-made Rat Vegfb siRNA oligo Duplex | 89811 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo22340 | Pre-made Mouse Vegfb/Vrf/VEGF-B siRNA oligo Duplex | 22340 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo722115 | Pre-made Cynomolgus/Rhesus macaque VEGFB siRNA oligo Duplex | 722115 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092465 | Pre-made Cat/Feline VEGFB siRNA oligo Duplex | 101092465 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476036 | Pre-made Dog/Canine VEGFB siRNA oligo Duplex | 476036 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282121 | Pre-made Bovines/Cattle VEGFB siRNA oligo Duplex | 282121 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055238 | Pre-made Equine/Horse VEGFB siRNA oligo Duplex | 100055238 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
VEGFB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T30040-Ab | Human | Anti-Human VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T30040-Ab | Rat | Anti-Rat VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T30040-Ab | Mouse | Anti-Mouse VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T30040-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T30040-Ab | Cat/Feline | Anti-Cat/Feline VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T30040-Ab | Dog/Canine | Anti-Dog/Canine VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T30040-Ab | Bovines/Cattle | Anti-Bovines/Cattle VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T30040-Ab | Equine/Horse | Anti-Equine/Horse VEGFB monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
VEGFB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T30040-Ag | Human | Human VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T30040-Ag | Rat | Rat VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T30040-Ag | Mouse | Mouse VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T30040-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T30040-Ag | Cat/Feline | Cat/Feline VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T30040-Ag | Dog/Canine | Dog/Canine VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T30040-Ag | Bovines/Cattle | Bovines/Cattle VEGFB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T30040-Ag | Equine/Horse | Equine/Horse VEGFB recombinant protein | Mammalian cell | Detail |
