Explore Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
| Target ID |
GM-T29879
|
| Target Name |
Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3678
|
| Gene ID |
100064655 (Equus caballus), 101093870 (Felis catus), 16402 (Mus musculus), 281873 (Bos taurus) 315346 (Rattus norvegicus), 3678 (Homo sapiens), 486493 (Canis lupus familiaris), 574315 (Macaca mulatta)
|
| Target Alternative Names |
CD49 antigen-like family member E,CD49e,Cd49e,FNRA,Fibronectin receptor subunit alpha,Fnra,ITGA5,Integrin Alpha 5,Integrin alpha-5,Integrin alpha-F,Itga5,Itga5_retired,VLA-5,VLA5,VLA5A
|
| Uniprot Accession |
P11688,Q27977,P08648
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
Prostate Cancer
|
| Disease from KEGG |
Phagosome, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Pertussis, Yersinia infection, Human papillomavirus infection, Proteoglycans in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000024979, ENSMUSG00000000555, ENSBTAG00000013745, ENSG00000161638, ENSCAFG00845016791, ENSMMUG00000003755
|
Pre-made viral vector of Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e cDNA Clones/ORF Plasmid
Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3678 | Pre-made Human ITGA5/FNRA/CD49e siRNA oligo Duplex | 3678 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo315346 | Pre-made Rat Itga5/Itga5_retired siRNA oligo Duplex | 315346 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16402 | Pre-made Mouse Itga5/Fnra/VLA5 siRNA oligo Duplex | 16402 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574315 | Pre-made Cynomolgus/Rhesus macaque ITGA5 siRNA oligo Duplex | 574315 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093870 | Pre-made Cat/Feline ITGA5 siRNA oligo Duplex | 101093870 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486493 | Pre-made Dog/Canine ITGA5 siRNA oligo Duplex | 486493 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281873 | Pre-made Bovines/Cattle ITGA5 siRNA oligo Duplex | 281873 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064655 | Pre-made Equine/Horse ITGA5 siRNA oligo Duplex | 100064655 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29879-Ab | Human | Anti-Human Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T29879-Ab | Rat | Anti-Rat Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29879-Ab | Mouse | Anti-Mouse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T29879-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T29879-Ab | Cat/Feline | Anti-Cat/Feline Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29879-Ab | Dog/Canine | Anti-Dog/Canine Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T29879-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T29879-Ab | Equine/Horse | Anti-Equine/Horse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29879-Ag | Human | Human Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T29879-Ag | Rat | Rat Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T29879-Ag | Mouse | Mouse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T29879-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T29879-Ag | Cat/Feline | Cat/Feline Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T29879-Ag | Dog/Canine | Dog/Canine Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T29879-Ag | Bovines/Cattle | Bovines/Cattle Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T29879-Ag | Equine/Horse | Equine/Horse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle) | HEK293 | Products Developing |