Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Transmembrane Protein.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Target ID GM-T29879
Target Name Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e
Gene Group ldentifer
(Target Gene ID in Homo species)
3678
Gene ID 100064655 (Equus caballus), 101093870 (Felis catus), 16402 (Mus musculus), 281873 (Bos taurus)
315346 (Rattus norvegicus), 3678 (Homo sapiens), 486493 (Canis lupus familiaris), 574315 (Macaca mulatta)
Target Alternative Names CD49 antigen-like family member E,CD49e,Cd49e,FNRA,Fibronectin receptor subunit alpha,Fnra,ITGA5,Integrin Alpha 5,Integrin alpha-5,Integrin alpha-F,Itga5,Itga5_retired,VLA-5,VLA5,VLA5A
Uniprot Accession P11688,Q27977,P08648
Protein Sub-location Transmembrane Protein
Category Therapeutics Target, INN Index
Disease Prostate Cancer
Disease from KEGG Phagosome, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Pertussis, Yersinia infection, Human papillomavirus infection, Proteoglycans in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
Gene Ensembl ENSECAG00000024979, ENSMUSG00000000555, ENSBTAG00000013745, ENSG00000161638, ENSCAFG00845016791, ENSMMUG00000003755


Pre-made viral vector of Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP005090Human ITGA5/CD49e/FNRA Lentivirus plasmidNM_0022053678HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005090Human ITGA5/CD49e/FNRA Lentivirus particleNM_0022053678HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV000338Mouse Itga5/Cd49e/Fnra Adeno-associate virus(AAV) plasmidNM_010577.416402MouseAdeno-associate virus(AAV) plasmidNullHA (C-Terminal)CMVDetail
vGMAAV000338Mouse Itga5/Cd49e/Fnra Adeno-associate virus(AAV) particleNM_010577.416402MouseAdeno-associate virus(AAV) particleNullHA (C-Terminal)CMVDetail


Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo3678Pre-made Human ITGA5/FNRA/CD49e siRNA oligo Duplex3678HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo315346Pre-made Rat Itga5/Itga5_retired siRNA oligo Duplex315346RatIn-vitro grade; in-vivo gradeDetail
pGMoligo16402Pre-made Mouse Itga5/Fnra/VLA5 siRNA oligo Duplex16402MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo574315Pre-made Cynomolgus/Rhesus macaque ITGA5 siRNA oligo Duplex574315Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101093870Pre-made Cat/Feline ITGA5 siRNA oligo Duplex101093870Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo486493Pre-made Dog/Canine ITGA5 siRNA oligo Duplex486493Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo281873Pre-made Bovines/Cattle ITGA5 siRNA oligo Duplex281873Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100064655Pre-made Equine/Horse ITGA5 siRNA oligo Duplex100064655Equine/HorseIn-vitro grade; in-vivo gradeDetail


Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T29879-AbHumanAnti-Human Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-rg-T29879-AbRatAnti-Rat Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-mg-T29879-AbMouseAnti-Mouse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cynog-T29879-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-felg-T29879-AbCat/FelineAnti-Cat/Feline Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-cang-T29879-AbDog/CanineAnti-Dog/Canine Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-bovg-T29879-AbBovines/CattleAnti-Bovines/Cattle Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail
GM-Tg-equg-T29879-AbEquine/HorseAnti-Equine/Horse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e monoclonal antibodymabFACS/Biofunctional Antibody, Therapeutics Target antibodyDetail


Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)/protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T29879-AgHumanHuman Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-rg-T29879-AgRatRat Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-mg-T29879-AgMouseMouse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-cynog-T29879-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-felg-T29879-AgCat/FelineCat/Feline Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-cang-T29879-AgDog/CanineDog/Canine Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-bovg-T29879-AgBovines/CattleBovines/Cattle Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing
GM-Tg-equg-T29879-AgEquine/HorseEquine/Horse Integrin alpha-5/Integrin Alpha 5/ITGA5/CD49e VLP (virus-like particle)HEK293Products Developing