Explore LAMB3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T29736
|
| Target Name |
LAMB3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3914
|
| Gene ID |
100056564 (Equus caballus), 101088641 (Felis catus), 16780 (Mus musculus), 305078 (Rattus norvegicus)
3914 (Homo sapiens), 442953 (Canis lupus familiaris), 529939 (Bos taurus), 720945 (Macaca mulatta)
|
| Target Alternative Names |
AI1A,BM600-125KDA,Epiligrin subunit bata,JEB1A,JEB1B,Kalinin B1 chain,Kalinin subunit beta,LAM5,LAMB3,LAMNB1,Lamb3,Laminin B1k chain,Laminin subunit beta-3,Laminin-5 subunit beta,Nicein subunit beta
|
| Uniprot Accession |
Q61087,Q13751
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Toxoplasmosis, Amoebiasis, Human papillomavirus infection, Pathways in cancer, Small cell lung cancer
|
| Gene Ensembl |
ENSECAG00000008204, ENSMUSG00000026639, ENSG00000196878, ENSCAFG00845002662, ENSBTAG00000016542, ENSMMUG00000016925
|
LAMB3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3914 | Pre-made Human LAMB3/AI1A/LAM5 siRNA oligo Duplex | 3914 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305078 | Pre-made Rat Lamb3 siRNA oligo Duplex | 305078 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16780 | Pre-made Mouse Lamb3 siRNA oligo Duplex | 16780 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720945 | Pre-made Cynomolgus/Rhesus macaque LAMB3 siRNA oligo Duplex | 720945 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088641 | Pre-made Cat/Feline LAMB3 siRNA oligo Duplex | 101088641 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442953 | Pre-made Dog/Canine LAMB3 siRNA oligo Duplex | 442953 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529939 | Pre-made Bovines/Cattle LAMB3 siRNA oligo Duplex | 529939 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056564 | Pre-made Equine/Horse LAMB3 siRNA oligo Duplex | 100056564 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LAMB3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29736-Ab | Human | Anti-Human LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T29736-Ab | Rat | Anti-Rat LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29736-Ab | Mouse | Anti-Mouse LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T29736-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T29736-Ab | Cat/Feline | Anti-Cat/Feline LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29736-Ab | Dog/Canine | Anti-Dog/Canine LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T29736-Ab | Bovines/Cattle | Anti-Bovines/Cattle LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T29736-Ab | Equine/Horse | Anti-Equine/Horse LAMB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LAMB3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29736-Ag | Human | Human LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T29736-Ag | Rat | Rat LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T29736-Ag | Mouse | Mouse LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T29736-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T29736-Ag | Cat/Feline | Cat/Feline LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T29736-Ag | Dog/Canine | Dog/Canine LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T29736-Ag | Bovines/Cattle | Bovines/Cattle LAMB3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T29736-Ag | Equine/Horse | Equine/Horse LAMB3 recombinant protein | Mammalian cell | Detail |
