Explore ADRA1B gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T29500
|
| Target Name |
ADRA1B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
147
|
| Gene ID |
100071055 (Equus caballus), 101092238 (Felis catus), 11548 (Mus musculus), 147 (Homo sapiens)
24173 (Rattus norvegicus), 403962 (Canis lupus familiaris), 407140 (Bos taurus), 695106 (Macaca mulatta)
|
| Target Alternative Names |
ADRA1,ADRA1B,ALPHA1BAR,Adra1b,Alpha-1B adrenergic receptor,Alpha-1B adrenoreceptor (Alpha-1B adrenoceptor),RDC5,[a]1b
|
| Uniprot Accession |
P97717,P35368,P15823,P11615
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, Neuroactive ligand-receptor interaction, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Salivary secretion
|
| Gene Ensembl |
ENSECAG00000011653, ENSMUSG00000050541, ENSG00000170214, ENSCAFG00845001264, ENSBTAG00000040253, ENSMMUG00000050043
|
| Target Classification |
GPCR
|
Pre-made viral vector of ADRA1B cDNA Clones/ORF Plasmid
ADRA1B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo147 | Pre-made Human ADRA1B/ADRA1/ALPHA1BAR siRNA oligo Duplex | 147 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24173 | Pre-made Rat Adra1b siRNA oligo Duplex | 24173 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11548 | Pre-made Mouse Adra1b/[a]1b siRNA oligo Duplex | 11548 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695106 | Pre-made Cynomolgus/Rhesus macaque ADRA1B siRNA oligo Duplex | 695106 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092238 | Pre-made Cat/Feline ADRA1B siRNA oligo Duplex | 101092238 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403962 | Pre-made Dog/Canine ADRA1B/RDC5 siRNA oligo Duplex | 403962 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo407140 | Pre-made Bovines/Cattle ADRA1B siRNA oligo Duplex | 407140 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071055 | Pre-made Equine/Horse ADRA1B siRNA oligo Duplex | 100071055 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ADRA1B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29500-Ab | Human | Anti-Human ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T29500-Ab | Rat | Anti-Rat ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29500-Ab | Mouse | Anti-Mouse ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T29500-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T29500-Ab | Cat/Feline | Anti-Cat/Feline ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29500-Ab | Dog/Canine | Anti-Dog/Canine ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T29500-Ab | Bovines/Cattle | Anti-Bovines/Cattle ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T29500-Ab | Equine/Horse | Anti-Equine/Horse ADRA1B monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
ADRA1B VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29500-Ag | Human | Human ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T29500-Ag | Rat | Rat ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T29500-Ag | Mouse | Mouse ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T29500-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T29500-Ag | Cat/Feline | Cat/Feline ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T29500-Ag | Dog/Canine | Dog/Canine ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T29500-Ag | Bovines/Cattle | Bovines/Cattle ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T29500-Ag | Equine/Horse | Equine/Horse ADRA1B VLP (virus-like particle) | HEK293 | Products Developing |
