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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]
| Target ID |
GM-T29345
|
| Target Name |
MUC17
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
140453
|
| Gene ID |
119872384 (Canis lupus familiaris), 140453 (Homo sapiens), 666339 (Mus musculus)
|
| Target Alternative Names |
MUC-17,MUC-3,MUC17,MUC3,Muc17,Muc3,Mucin-17,Small intestinal mucin-3 (MUC-3)
|
| Uniprot Accession |
Q685J3
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Gene Ensembl |
ENSG00000169876, ENSMUSG00000037390
|
| Target Classification |
Tumor-associated antigen (TAA)
|
MUC17 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo140453 | Pre-made Human MUC17/MUC3/MUC-3 siRNA oligo Duplex | 140453 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo666339 | Pre-made Mouse Muc17/Muc3 siRNA oligo Duplex | 666339 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo119872384 | Pre-made Dog/Canine MUC17 siRNA oligo Duplex | 119872384 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
MUC17 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29345-Ab | Human | Anti-Human MUC17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29345-Ab | Mouse | Anti-Mouse MUC17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29345-Ab | Dog/Canine | Anti-Dog/Canine MUC17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
MUC17 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29345-Ag | Human | Human MUC17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T29345-Ag | Mouse | Mouse MUC17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T29345-Ag | Dog/Canine | Dog/Canine MUC17 VLP (virus-like particle) | HEK293 | Products Developing |
