Explore DDX58/RIG-1/RIGI gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020]
| Target ID |
GM-T29339
|
| Target Name |
DDX58/RIG-1/RIGI
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
23586
|
| Gene ID |
100067920 (Equus caballus), 100855560 (Canis lupus familiaris), 101095926 (Felis catus), 230073 (Mus musculus)
23586 (Homo sapiens), 297989 (Rattus norvegicus), 504760 (Bos taurus), 704638 (Macaca mulatta)
|
| Target Alternative Names |
6430573D20Rik,ATP-dependent RNA helicase DDX58,Antiviral innate immune response receptor RIG-I,C330021E21,DDX58,DEAD box protein 58,Ddx58,RIG-1,RIG-I,RIG-I-like receptor 1 (RLR-1),RIG1,RIGI,RLR-1,RNA sensor RIG-I,Retinoic acid-inducible gene 1 protein (RIG-1),Retinoic acid-inducible gene I protein (RIG-I),Rig1,Rigi,SGMRT2
|
| Uniprot Accession |
Q6Q899,O95786
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
NF-kappa B signaling pathway, RIG-I-like receptor signaling pathway, Hepatitis C, Hepatitis B, Measles, Influenza A, Epstein-Barr virus infection
|
| Gene Ensembl |
ENSECAG00000021989, ENSMUSG00000040296, ENSG00000107201, ENSBTAG00000003366, ENSMMUG00000012442
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of DDX58/RIG-1/RIGI cDNA Clones/ORF Plasmid
DDX58/RIG-1/RIGI siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23586 | Pre-made Human RIGI/RIG1/DDX58 siRNA oligo Duplex | 23586 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo297989 | Pre-made Rat Rig1/Ddx58 siRNA oligo Duplex | 297989 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo230073 | Pre-made Mouse Rigi/Ddx58/RIG-I siRNA oligo Duplex | 230073 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704638 | Pre-made Cynomolgus/Rhesus macaque RIGI/DDX58 siRNA oligo Duplex | 704638 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095926 | Pre-made Cat/Feline RIGI/DDX58 siRNA oligo Duplex | 101095926 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100855560 | Pre-made Dog/Canine RIGI/DDX58 siRNA oligo Duplex | 100855560 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504760 | Pre-made Bovines/Cattle RIGI/DDX58 siRNA oligo Duplex | 504760 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067920 | Pre-made Equine/Horse RIGI/DDX58 siRNA oligo Duplex | 100067920 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DDX58/RIG-1/RIGI antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T29339-Ab | Human | Anti-Human DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T29339-Ab | Rat | Anti-Rat DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T29339-Ab | Mouse | Anti-Mouse DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T29339-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T29339-Ab | Cat/Feline | Anti-Cat/Feline DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T29339-Ab | Dog/Canine | Anti-Dog/Canine DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T29339-Ab | Bovines/Cattle | Anti-Bovines/Cattle DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T29339-Ab | Equine/Horse | Anti-Equine/Horse DDX58/RIG-1/RIGI monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
DDX58/RIG-1/RIGI VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T29339-Ag | Human | Human DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T29339-Ag | Rat | Rat DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T29339-Ag | Mouse | Mouse DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T29339-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T29339-Ag | Cat/Feline | Cat/Feline DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T29339-Ag | Dog/Canine | Dog/Canine DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T29339-Ag | Bovines/Cattle | Bovines/Cattle DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T29339-Ag | Equine/Horse | Equine/Horse DDX58/RIG-1/RIGI VLP (virus-like particle) | HEK293 | Products Developing |
