Explore CHRM1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T28893
|
| Target Name |
CHRM1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1128
|
| Gene ID |
100064117 (Equus caballus), 101093801 (Felis catus), 1128 (Homo sapiens), 12669 (Mus musculus)
25229 (Rattus norvegicus), 281684 (Bos taurus), 483776 (Canis lupus familiaris), 574362 (Macaca mulatta)
|
| Target Alternative Names |
CHRM1,Chrm-1,Chrm1,HM1,M1,M1R,Muscarinic acetylcholine receptor M1
|
| Uniprot Accession |
P11229,P12657,P08482,P56489
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Cholinergic synapse, Regulation of actin cytoskeleton, Alzheimer disease
|
| Gene Ensembl |
ENSECAG00000005493, ENSG00000168539, ENSMUSG00000032773, ENSBTAG00000011579, ENSCAFG00845007309, ENSMMUG00000017292
|
| Target Classification |
GPCR
|
Pre-made viral vector of CHRM1 cDNA Clones/ORF Plasmid
CHRM1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1128 | Pre-made Human CHRM1/M1/HM1 siRNA oligo Duplex | 1128 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25229 | Pre-made Rat Chrm1 siRNA oligo Duplex | 25229 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12669 | Pre-made Mouse Chrm1/M1/M1R siRNA oligo Duplex | 12669 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574362 | Pre-made Cynomolgus/Rhesus macaque CHRM1/M1 siRNA oligo Duplex | 574362 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093801 | Pre-made Cat/Feline CHRM1 siRNA oligo Duplex | 101093801 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483776 | Pre-made Dog/Canine CHRM1 siRNA oligo Duplex | 483776 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281684 | Pre-made Bovines/Cattle CHRM1 siRNA oligo Duplex | 281684 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064117 | Pre-made Equine/Horse CHRM1 siRNA oligo Duplex | 100064117 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CHRM1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28893-Ab | Human | Anti-Human CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28893-Ab | Rat | Anti-Rat CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28893-Ab | Mouse | Anti-Mouse CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28893-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28893-Ab | Cat/Feline | Anti-Cat/Feline CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28893-Ab | Dog/Canine | Anti-Dog/Canine CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28893-Ab | Bovines/Cattle | Anti-Bovines/Cattle CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28893-Ab | Equine/Horse | Anti-Equine/Horse CHRM1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CHRM1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28893-Ag | Human | Human CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T28893-Ag | Rat | Rat CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T28893-Ag | Mouse | Mouse CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T28893-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T28893-Ag | Cat/Feline | Cat/Feline CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T28893-Ag | Dog/Canine | Dog/Canine CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T28893-Ag | Bovines/Cattle | Bovines/Cattle CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T28893-Ag | Equine/Horse | Equine/Horse CHRM1 VLP (virus-like particle) | HEK293 | Products Developing |
