Explore HDAC8 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-T28887
|
| Target Name |
HDAC8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
55869
|
| Gene ID |
100052401 (Equus caballus), 101096383 (Felis catus), 363481 (Rattus norvegicus), 480957 (Canis lupus familiaris)
540666 (Bos taurus), 55869 (Homo sapiens), 699642 (Macaca mulatta), 70315 (Mus musculus)
|
| Target Alternative Names |
2610007D20Rik,CDA07,CDLS5,HD8,HDAC8,HDACL1,Hdac8,Histone deacetylase 8,KDAC8,MRXS6,Protein deacetylase HDAC8,Protein decrotonylase HDAC8,RGD1562895,RPD3,WTS
|
| Uniprot Accession |
B1WC68,Q0VCB2,Q9BY41,Q8VH37
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000018525, ENSCAFG00845020238, ENSBTAG00000046092, ENSG00000147099, ENSMMUG00000003296, ENSMUSG00000067567
|
Pre-made viral vector of HDAC8 cDNA Clones/ORF Plasmid
HDAC8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55869 | Pre-made Human HDAC8/HD8/WTS siRNA oligo Duplex | 55869 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363481 | Pre-made Rat Hdac8/HD8/RGD1562895 siRNA oligo Duplex | 363481 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo70315 | Pre-made Mouse Hdac8/2610007D20Rik siRNA oligo Duplex | 70315 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699642 | Pre-made Cynomolgus/Rhesus macaque HDAC8 siRNA oligo Duplex | 699642 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096383 | Pre-made Cat/Feline HDAC8 siRNA oligo Duplex | 101096383 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480957 | Pre-made Dog/Canine HDAC8 siRNA oligo Duplex | 480957 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540666 | Pre-made Bovines/Cattle HDAC8 siRNA oligo Duplex | 540666 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052401 | Pre-made Equine/Horse HDAC8 siRNA oligo Duplex | 100052401 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HDAC8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28887-Ab | Human | Anti-Human HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28887-Ab | Rat | Anti-Rat HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28887-Ab | Mouse | Anti-Mouse HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28887-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28887-Ab | Cat/Feline | Anti-Cat/Feline HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28887-Ab | Dog/Canine | Anti-Dog/Canine HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28887-Ab | Bovines/Cattle | Anti-Bovines/Cattle HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28887-Ab | Equine/Horse | Anti-Equine/Horse HDAC8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
HDAC8 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28887-Ag | Human | Human HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T28887-Ag | Rat | Rat HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T28887-Ag | Mouse | Mouse HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T28887-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T28887-Ag | Cat/Feline | Cat/Feline HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T28887-Ag | Dog/Canine | Dog/Canine HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T28887-Ag | Bovines/Cattle | Bovines/Cattle HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T28887-Ag | Equine/Horse | Equine/Horse HDAC8 VLP (virus-like particle) | HEK293 | Products Developing |
