Explore EPHA1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T28418
|
| Target Name |
EPHA1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2041
|
| Gene ID |
100056221 (Equus caballus), 101100200 (Felis catus), 13835 (Mus musculus), 2041 (Homo sapiens)
312279 (Rattus norvegicus), 482735 (Canis lupus familiaris), 525946 (Bos taurus), 706295 (Macaca mulatta)
|
| Target Alternative Names |
EPHA1,Epha1,Eph,Esk,5730453L17Rik,EPH,EPHT,EPHT1
|
| Uniprot Accession |
Q60750,P21709
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Axon guidance
|
| Gene Ensembl |
ENSECAG00000023882, ENSMUSG00000029859, ENSG00000146904, ENSCAFG00845013685, ENSBTAG00000006359, ENSMMUG00000055322
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of EPHA1 cDNA Clones/ORF Plasmid
EPHA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2041 | Pre-made Human EPHA1/EPH/EPHT siRNA oligo Duplex | 2041 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312279 | Pre-made Rat Epha1 siRNA oligo Duplex | 312279 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13835 | Pre-made Mouse Epha1/Eph/Esk siRNA oligo Duplex | 13835 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706295 | Pre-made Cynomolgus/Rhesus macaque EPHA1 siRNA oligo Duplex | 706295 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100200 | Pre-made Cat/Feline EPHA1 siRNA oligo Duplex | 101100200 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482735 | Pre-made Dog/Canine EPHA1 siRNA oligo Duplex | 482735 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525946 | Pre-made Bovines/Cattle EPHA1 siRNA oligo Duplex | 525946 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056221 | Pre-made Equine/Horse EPHA1 siRNA oligo Duplex | 100056221 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EPHA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28418-Ab | Human | Anti-Human EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28418-Ab | Rat | Anti-Rat EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28418-Ab | Mouse | Anti-Mouse EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28418-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28418-Ab | Cat/Feline | Anti-Cat/Feline EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28418-Ab | Dog/Canine | Anti-Dog/Canine EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28418-Ab | Bovines/Cattle | Anti-Bovines/Cattle EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28418-Ab | Equine/Horse | Anti-Equine/Horse EPHA1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EPHA1 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28418-Ag | Human | Human EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T28418-Ag | Rat | Rat EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T28418-Ag | Mouse | Mouse EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T28418-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T28418-Ag | Cat/Feline | Cat/Feline EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T28418-Ag | Dog/Canine | Dog/Canine EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T28418-Ag | Bovines/Cattle | Bovines/Cattle EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T28418-Ag | Equine/Horse | Equine/Horse EPHA1 VLP (virus-like particle) | HEK293 | Products Developing |
