Explore CDH11/Cadherin-11 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T28385
|
| Target Name |
CDH11/Cadherin-11
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1009
|
| Gene ID |
100052714 (Equus caballus), 1009 (Homo sapiens), 12552 (Mus musculus), 479696 (Canis lupus familiaris)
708826 (Macaca mulatta), 785475 (Bos taurus), 84407 (Rattus norvegicus)
|
| Target Alternative Names |
CAD11,CDH11,CDHOB,Cad11,Cadherin-11,Cdh11,ESWS,OB,OSF-4,Osteoblast cadherin (OB-cadherin),TBHS2
|
| Uniprot Accession |
P55287,P55288
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Renal fibrosis, Congenital occlusion of ureteropelvic junction
|
| Gene Ensembl |
ENSECAG00000008823, ENSG00000140937, ENSMUSG00000031673, ENSCAFG00845012172, ENSMMUG00000005520, ENSBTAG00000032092
|
Pre-made viral vector of CDH11/Cadherin-11 cDNA Clones/ORF Plasmid
CDH11/Cadherin-11 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1009 | Pre-made Human CDH11/OB/ESWS siRNA oligo Duplex | 1009 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84407 | Pre-made Rat Cdh11 siRNA oligo Duplex | 84407 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12552 | Pre-made Mouse Cdh11/Cad11/OSF-4 siRNA oligo Duplex | 12552 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708826 | Pre-made Cynomolgus/Rhesus macaque CDH11 siRNA oligo Duplex | 708826 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479696 | Pre-made Dog/Canine CDH11 siRNA oligo Duplex | 479696 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo785475 | Pre-made Bovines/Cattle CDH11 siRNA oligo Duplex | 785475 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052714 | Pre-made Equine/Horse CDH11 siRNA oligo Duplex | 100052714 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CDH11/Cadherin-11 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28385-Ab | Human | Anti-Human CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28385-Ab | Rat | Anti-Rat CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28385-Ab | Mouse | Anti-Mouse CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28385-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28385-Ab | Dog/Canine | Anti-Dog/Canine CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28385-Ab | Bovines/Cattle | Anti-Bovines/Cattle CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28385-Ab | Equine/Horse | Anti-Equine/Horse CDH11/Cadherin-11 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CDH11/Cadherin-11 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28385-Ag | Human | Human CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T28385-Ag | Rat | Rat CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T28385-Ag | Mouse | Mouse CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T28385-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T28385-Ag | Dog/Canine | Dog/Canine CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T28385-Ag | Bovines/Cattle | Bovines/Cattle CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T28385-Ag | Equine/Horse | Equine/Horse CDH11/Cadherin-11 VLP (virus-like particle) | HEK293 | Products Developing |
