Explore CCKAR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T28330
|
| Target Name |
CCKAR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
886
|
| Gene ID |
100055506 (Equus caballus), 101099960 (Felis catus), 12425 (Mus musculus), 24889 (Rattus norvegicus)
488846 (Canis lupus familiaris), 506207 (Bos taurus), 694742 (Macaca mulatta), 886 (Homo sapiens)
|
| Target Alternative Names |
CCK-1R,CCK-A,CCK-A receptor,CCK-AR,CCK1-R,CCK1R,CCKAR,CCKRA,Cck-ar,Cckar,Cholecystokinin receptor type A,Cholecystokinin-1 receptor (CCK1-R)
|
| Uniprot Accession |
O08786,P30551,Q5D0K2,P32238
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Calcium signaling pathway, Neuroactive ligand-receptor interaction, Insulin secretion, Pancreatic secretion
|
| Gene Ensembl |
ENSECAG00000017266, ENSMUSG00000029193, ENSCAFG00845005880, ENSBTAG00000004988, ENSMMUG00000049298, ENSG00000163394
|
| Target Classification |
GPCR
|
Pre-made viral vector of CCKAR cDNA Clones/ORF Plasmid
CCKAR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo886 | Pre-made Human CCKAR/CCK-A/CCK1R siRNA oligo Duplex | 886 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24889 | Pre-made Rat Cckar/Cck-ar siRNA oligo Duplex | 24889 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12425 | Pre-made Mouse Cckar siRNA oligo Duplex | 12425 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694742 | Pre-made Cynomolgus/Rhesus macaque CCKAR siRNA oligo Duplex | 694742 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099960 | Pre-made Cat/Feline CCKAR siRNA oligo Duplex | 101099960 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488846 | Pre-made Dog/Canine CCKAR siRNA oligo Duplex | 488846 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506207 | Pre-made Bovines/Cattle CCKAR siRNA oligo Duplex | 506207 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055506 | Pre-made Equine/Horse CCKAR siRNA oligo Duplex | 100055506 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CCKAR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T28330-Ab | Human | Anti-Human CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T28330-Ab | Rat | Anti-Rat CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T28330-Ab | Mouse | Anti-Mouse CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T28330-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T28330-Ab | Cat/Feline | Anti-Cat/Feline CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T28330-Ab | Dog/Canine | Anti-Dog/Canine CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T28330-Ab | Bovines/Cattle | Anti-Bovines/Cattle CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T28330-Ab | Equine/Horse | Anti-Equine/Horse CCKAR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CCKAR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T28330-Ag | Human | Human CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T28330-Ag | Rat | Rat CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T28330-Ag | Mouse | Mouse CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T28330-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T28330-Ag | Cat/Feline | Cat/Feline CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T28330-Ag | Dog/Canine | Dog/Canine CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T28330-Ag | Bovines/Cattle | Bovines/Cattle CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T28330-Ag | Equine/Horse | Equine/Horse CCKAR VLP (virus-like particle) | HEK293 | Products Developing |
