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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017]
| Target ID |
GM-T27918
|
| Target Name |
DDX5
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1655
|
| Gene ID |
100064168 (Equus caballus), 101099414 (Felis catus), 13207 (Mus musculus), 1655 (Homo sapiens) 287765 (Rattus norvegicus), 480472 (Canis lupus familiaris), 533700 (Bos taurus), 677694 (Macaca mulatta)
|
| Target Alternative Names |
2600009A06Rik,DDX5,DEAD box protein 5,Ddx5,G17P1,HLR1,HUMP68,Hlr1,Probable ATP-dependent RNA helicase DDX5,RNA helicase p68,p68
|
| Uniprot Accession |
Q61656,P17844
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Proteoglycans in cancer
|
| Gene Ensembl |
ENSECAG00000011132, ENSMUSG00000020719, ENSG00000108654, ENSCAFG00845023472, ENSBTAG00000018423, ENSMMUG00000009463
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of DDX5 cDNA Clones/ORF Plasmid
DDX5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1655 | Pre-made Human DDX5/p68/HLR1 siRNA oligo Duplex | 1655 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo287765 | Pre-made Rat Ddx5 siRNA oligo Duplex | 287765 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13207 | Pre-made Mouse Ddx5/p68/Hlr1 siRNA oligo Duplex | 13207 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo677694 | Pre-made Cynomolgus/Rhesus macaque DDX5 siRNA oligo Duplex | 677694 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099414 | Pre-made Cat/Feline DDX5 siRNA oligo Duplex | 101099414 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo480472 | Pre-made Dog/Canine DDX5 siRNA oligo Duplex | 480472 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533700 | Pre-made Bovines/Cattle DDX5 siRNA oligo Duplex | 533700 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064168 | Pre-made Equine/Horse DDX5 siRNA oligo Duplex | 100064168 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DDX5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T27918-Ab | Human | Anti-Human DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T27918-Ab | Rat | Anti-Rat DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T27918-Ab | Mouse | Anti-Mouse DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T27918-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T27918-Ab | Cat/Feline | Anti-Cat/Feline DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T27918-Ab | Dog/Canine | Anti-Dog/Canine DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T27918-Ab | Bovines/Cattle | Anti-Bovines/Cattle DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T27918-Ab | Equine/Horse | Anti-Equine/Horse DDX5 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DDX5 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T27918-Ag | Human | Human DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T27918-Ag | Rat | Rat DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T27918-Ag | Mouse | Mouse DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T27918-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T27918-Ag | Cat/Feline | Cat/Feline DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T27918-Ag | Dog/Canine | Dog/Canine DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T27918-Ag | Bovines/Cattle | Bovines/Cattle DDX5 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T27918-Ag | Equine/Horse | Equine/Horse DDX5 recombinant protein | Mammalian cell | Detail |