Explore BMP9/GDF2 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T27611
|
| Target Name |
BMP9/GDF2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
2658
|
| Gene ID |
100051984 (Equus caballus), 101087270 (Felis catus), 12165 (Mus musculus), 2658 (Homo sapiens) 290921 (Rattus norvegicus), 540384 (Bos taurus), 611149 (Canis lupus familiaris), 711516 (Macaca mulatta)
|
| Target Alternative Names |
BMP-9,BMP9,Bmp9,Bone morphogenetic protein 9 (BMP-9),GDF-2,GDF2,Gdf2,Growth/differentiation factor 2,HHT5
|
| Uniprot Accession |
Q9WV56,Q9UK05
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSECAG00000012596, ENSMUSG00000072625, ENSG00000263761, ENSBTAG00000005004, ENSCAFG00845008392, ENSMMUG00000055320
|
Pre-made viral vector of BMP9/GDF2 cDNA Clones/ORF Plasmid
BMP9/GDF2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2658 | Pre-made Human GDF2/BMP9/HHT5 siRNA oligo Duplex | 2658 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo290921 | Pre-made Rat Gdf2 siRNA oligo Duplex | 290921 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12165 | Pre-made Mouse Gdf2/Bmp9 siRNA oligo Duplex | 12165 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711516 | Pre-made Cynomolgus/Rhesus macaque GDF2 siRNA oligo Duplex | 711516 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087270 | Pre-made Cat/Feline GDF2 siRNA oligo Duplex | 101087270 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611149 | Pre-made Dog/Canine GDF2 siRNA oligo Duplex | 611149 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540384 | Pre-made Bovines/Cattle GDF2 siRNA oligo Duplex | 540384 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051984 | Pre-made Equine/Horse GDF2 siRNA oligo Duplex | 100051984 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BMP9/GDF2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T27611-Ab | Human | Anti-Human BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T27611-Ab | Rat | Anti-Rat BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T27611-Ab | Mouse | Anti-Mouse BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T27611-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T27611-Ab | Cat/Feline | Anti-Cat/Feline BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T27611-Ab | Dog/Canine | Anti-Dog/Canine BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T27611-Ab | Bovines/Cattle | Anti-Bovines/Cattle BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T27611-Ab | Equine/Horse | Anti-Equine/Horse BMP9/GDF2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
BMP9/GDF2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T27611-Ag | Human | Human BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T27611-Ag | Rat | Rat BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T27611-Ag | Mouse | Mouse BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T27611-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T27611-Ag | Cat/Feline | Cat/Feline BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T27611-Ag | Dog/Canine | Dog/Canine BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T27611-Ag | Bovines/Cattle | Bovines/Cattle BMP9/GDF2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T27611-Ag | Equine/Horse | Equine/Horse BMP9/GDF2 recombinant protein | Mammalian cell | Detail |