Explore GABRD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T27376
|
| Target Name |
GABRD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2563
|
| Gene ID |
100064300 (Equus caballus), 101087589 (Felis catus), 14403 (Mus musculus), 2563 (Homo sapiens)
29689 (Rattus norvegicus), 489609 (Canis lupus familiaris), 508711 (Bos taurus), 710062 (Macaca mulatta)
|
| Target Alternative Names |
EIG10,EJM7,GABA(A) receptor subunit delta (GABAAR subunit delta),GABAA-RD,GABAARdelta,GABRD,GEFSP5,Gabrd,Gamma-aminobutyric acid receptor subunit delta
|
| Uniprot Accession |
P22933,O14764,P18506
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GABAergic synapse, Morphine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000043104, ENSMUSG00000029054, ENSG00000187730, ENSCAFG00845016184, ENSBTAG00000008672, ENSMMUG00000019086
|
Pre-made viral vector of GABRD cDNA Clones/ORF Plasmid
GABRD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2563 | Pre-made Human GABRD/EJM7/EIG10 siRNA oligo Duplex | 2563 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29689 | Pre-made Rat Gabrd/GABAA-RD siRNA oligo Duplex | 29689 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14403 | Pre-made Mouse Gabrd siRNA oligo Duplex | 14403 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710062 | Pre-made Cynomolgus/Rhesus macaque GABRD siRNA oligo Duplex | 710062 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087589 | Pre-made Cat/Feline GABRD siRNA oligo Duplex | 101087589 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489609 | Pre-made Dog/Canine GABRD siRNA oligo Duplex | 489609 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508711 | Pre-made Bovines/Cattle GABRD siRNA oligo Duplex | 508711 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064300 | Pre-made Equine/Horse GABRD siRNA oligo Duplex | 100064300 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABRD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T27376-Ab | Human | Anti-Human GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T27376-Ab | Rat | Anti-Rat GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T27376-Ab | Mouse | Anti-Mouse GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T27376-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T27376-Ab | Cat/Feline | Anti-Cat/Feline GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T27376-Ab | Dog/Canine | Anti-Dog/Canine GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T27376-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T27376-Ab | Equine/Horse | Anti-Equine/Horse GABRD monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABRD VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T27376-Ag | Human | Human GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T27376-Ag | Rat | Rat GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T27376-Ag | Mouse | Mouse GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T27376-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T27376-Ag | Cat/Feline | Cat/Feline GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T27376-Ag | Dog/Canine | Dog/Canine GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T27376-Ag | Bovines/Cattle | Bovines/Cattle GABRD VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T27376-Ag | Equine/Horse | Equine/Horse GABRD VLP (virus-like particle) | HEK293 | Products Developing |
