Explore BCL11A gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T26470
|
| Target Name |
BCL11A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
53335
|
| Gene ID |
100065364 (Equus caballus), 101098704 (Felis catus), 14025 (Mus musculus), 305589 (Rattus norvegicus)
481381 (Canis lupus familiaris), 53335 (Homo sapiens), 538680 (Bos taurus), 717675 (Macaca mulatta)
|
| Target Alternative Names |
BCL11A,Bcl11a,Evi9,Ctip1,Evi9a,Evi9b,Evi9c,BCL-11A,mKIAA1809,2810047E18Rik,D930021L15Rik,EVI9,CTIP1,DILOS,ZNF856,HBFQTL5,SMARCM1
|
| Uniprot Accession |
Q9QYE3,Q9H165
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000008094, ENSMUSG00000000861, ENSCAFG00845012955, ENSG00000119866, ENSBTAG00000016534, ENSMMUG00000011303
|
| Target Classification |
|
BCL11A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo53335 | Pre-made Human BCL11A/EVI9/CTIP1 siRNA oligo Duplex | 53335 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo305589 | Pre-made Rat Bcl11a siRNA oligo Duplex | 305589 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14025 | Pre-made Mouse Bcl11a/Evi9/Ctip1 siRNA oligo Duplex | 14025 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717675 | Pre-made Cynomolgus/Rhesus macaque BCL11A siRNA oligo Duplex | 717675 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098704 | Pre-made Cat/Feline BCL11A siRNA oligo Duplex | 101098704 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481381 | Pre-made Dog/Canine BCL11A siRNA oligo Duplex | 481381 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo538680 | Pre-made Bovines/Cattle BCL11A siRNA oligo Duplex | 538680 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100065364 | Pre-made Equine/Horse BCL11A siRNA oligo Duplex | 100065364 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BCL11A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26470-Ab | Human | Anti-Human BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26470-Ab | Rat | Anti-Rat BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26470-Ab | Mouse | Anti-Mouse BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26470-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26470-Ab | Cat/Feline | Anti-Cat/Feline BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26470-Ab | Dog/Canine | Anti-Dog/Canine BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26470-Ab | Bovines/Cattle | Anti-Bovines/Cattle BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26470-Ab | Equine/Horse | Anti-Equine/Horse BCL11A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BCL11A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26470-Ag | Human | Human BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T26470-Ag | Rat | Rat BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T26470-Ag | Mouse | Mouse BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T26470-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T26470-Ag | Cat/Feline | Cat/Feline BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T26470-Ag | Dog/Canine | Dog/Canine BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T26470-Ag | Bovines/Cattle | Bovines/Cattle BCL11A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T26470-Ag | Equine/Horse | Equine/Horse BCL11A recombinant protein | Mammalian cell | Detail |
