Explore CD61/Integrin beta 3/ITGB3 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T26457
|
| Target Name |
CD61/Integrin beta 3/ITGB3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3690
|
| Gene ID |
100009709 (Equus caballus), 101092159 (Felis catus), 16416 (Mus musculus), 282642 (Bos taurus) 29302 (Rattus norvegicus), 3690 (Homo sapiens), 403788 (Canis lupus familiaris), 717379 (Macaca mulatta)
|
| Target Alternative Names |
BDPLT16,BDPLT2,BDPLT24,CD61,GP3A,GPIIIA,GPIIIa,GT,GT2,INGRB3,INTB3,ITGB3,Integrin beta 3,Integrin beta-3,Itgb3,Platelet membrane glycoprotein IIIa (GPIIIa)
|
| Uniprot Accession |
O54890,Q8R2H2,P05106
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer, Prostate Cancer, Kidney transplant rejection
|
| Disease from KEGG |
Rap1 signaling pathway, Phagosome, PI3K-Akt signaling pathway, Osteoclast differentiation, Focal adhesion, ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Thyroid hormone signaling pathway, Human cytomegalovirus infection, Human papillomavirus infection, Proteoglycans in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000017625, ENSMUSG00000020689, ENSBTAG00000009987, ENSG00000259207, ENSCAFG00845021351, ENSMMUG00000003289
|
Pre-made viral vector of CD61/Integrin beta 3/ITGB3 cDNA Clones/ORF Plasmid
CD61/Integrin beta 3/ITGB3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3690 | Pre-made Human ITGB3/GT/GT2 siRNA oligo Duplex | 3690 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29302 | Pre-made Rat Itgb3/GPIIIa siRNA oligo Duplex | 29302 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16416 | Pre-made Mouse Itgb3/CD61/GP3A siRNA oligo Duplex | 16416 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717379 | Pre-made Cynomolgus/Rhesus macaque ITGB3 siRNA oligo Duplex | 717379 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092159 | Pre-made Cat/Feline ITGB3 siRNA oligo Duplex | 101092159 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403788 | Pre-made Dog/Canine ITGB3/GPIIIA siRNA oligo Duplex | 403788 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282642 | Pre-made Bovines/Cattle ITGB3/INTB3 siRNA oligo Duplex | 282642 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009709 | Pre-made Equine/Horse ITGB3 siRNA oligo Duplex | 100009709 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD61/Integrin beta 3/ITGB3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26457-Ab | Human | Anti-Human CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26457-Ab | Rat | Anti-Rat CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26457-Ab | Mouse | Anti-Mouse CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26457-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26457-Ab | Cat/Feline | Anti-Cat/Feline CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26457-Ab | Dog/Canine | Anti-Dog/Canine CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26457-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26457-Ab | Equine/Horse | Anti-Equine/Horse CD61/Integrin beta 3/ITGB3 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD61/Integrin beta 3/ITGB3 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26457-Ag | Human | Human CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T26457-Ag | Rat | Rat CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T26457-Ag | Mouse | Mouse CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T26457-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T26457-Ag | Cat/Feline | Cat/Feline CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T26457-Ag | Dog/Canine | Dog/Canine CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T26457-Ag | Bovines/Cattle | Bovines/Cattle CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T26457-Ag | Equine/Horse | Equine/Horse CD61/Integrin beta 3/ITGB3 VLP (virus-like particle) | HEK293 | Products Developing |