Explore GABRA5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T26368
|
| Target Name |
GABRA5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2558
|
| Gene ID |
100050880 (Equus caballus), 101090773 (Felis catus), 110886 (Mus musculus), 2558 (Homo sapiens)
29707 (Rattus norvegicus), 488688 (Canis lupus familiaris), 523515 (Bos taurus), 711838 (Macaca mulatta)
|
| Target Alternative Names |
A230018I05Rik,DEE79,EIEE79,GABA(A) receptor subunit alpha-5 (GABAAR subunit alpha-5),GABRA5,Gabra5,Gamma-aminobutyric acid receptor subunit alpha-5
|
| Uniprot Accession |
Q8BHJ7,P31644,P19969,Q08E50
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, GABAergic synapse, Taste transduction, Morphine addiction, Nicotine addiction
|
| Gene Ensembl |
ENSECAG00000005559, ENSMUSG00000055078, ENSG00000186297, ENSCAFG00845017763, ENSBTAG00000003392, ENSMMUG00000023554
|
Pre-made viral vector of GABRA5 cDNA Clones/ORF Plasmid
GABRA5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2558 | Pre-made Human GABRA5/DEE79/EIEE79 siRNA oligo Duplex | 2558 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29707 | Pre-made Rat Gabra5 siRNA oligo Duplex | 29707 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo110886 | Pre-made Mouse Gabra5/A230018I05Rik siRNA oligo Duplex | 110886 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711838 | Pre-made Cynomolgus/Rhesus macaque GABRA5 siRNA oligo Duplex | 711838 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101090773 | Pre-made Cat/Feline GABRA5 siRNA oligo Duplex | 101090773 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488688 | Pre-made Dog/Canine GABRA5 siRNA oligo Duplex | 488688 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523515 | Pre-made Bovines/Cattle GABRA5 siRNA oligo Duplex | 523515 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050880 | Pre-made Equine/Horse GABRA5 siRNA oligo Duplex | 100050880 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GABRA5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26368-Ab | Human | Anti-Human GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26368-Ab | Rat | Anti-Rat GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26368-Ab | Mouse | Anti-Mouse GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26368-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26368-Ab | Cat/Feline | Anti-Cat/Feline GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26368-Ab | Dog/Canine | Anti-Dog/Canine GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26368-Ab | Bovines/Cattle | Anti-Bovines/Cattle GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26368-Ab | Equine/Horse | Anti-Equine/Horse GABRA5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
GABRA5 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26368-Ag | Human | Human GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T26368-Ag | Rat | Rat GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T26368-Ag | Mouse | Mouse GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T26368-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T26368-Ag | Cat/Feline | Cat/Feline GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T26368-Ag | Dog/Canine | Dog/Canine GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T26368-Ag | Bovines/Cattle | Bovines/Cattle GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T26368-Ag | Equine/Horse | Equine/Horse GABRA5 VLP (virus-like particle) | HEK293 | Products Developing |
