Explore PRLR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
| Target ID |
GM-T26226
|
| Target Name |
PRLR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5618
|
| Gene ID |
100053793 (Equus caballus), 101101444 (Felis catus), 19116 (Mus musculus), 24684 (Rattus norvegicus)
281422 (Bos taurus), 479363 (Canis lupus familiaris), 5618 (Homo sapiens), 699369 (Macaca mulatta)
|
| Target Alternative Names |
HPRL,MFAB,PRL-R,PRLR,Pr-1,Pr-3,Prlr,Prlr-rs1,Prolactin receptor,RATPRLR,RI-PRLR,SPRLR,hPRLrI
|
| Uniprot Accession |
Q08501,P05710,Q28172,P16471
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Prolactin signaling pathway
|
| Gene Ensembl |
ENSECAG00000009483, ENSMUSG00000005268, ENSBTAG00000025035, ENSCAFG00845000774, ENSG00000113494, ENSMMUG00000006302
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
Pre-made viral vector of PRLR cDNA Clones/ORF Plasmid
PRLR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5618 | Pre-made Human PRLR/HPRL/MFAB siRNA oligo Duplex | 5618 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24684 | Pre-made Rat Prlr/RATPRLR siRNA oligo Duplex | 24684 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19116 | Pre-made Mouse Prlr/Pr-1/Pr-3 siRNA oligo Duplex | 19116 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699369 | Pre-made Cynomolgus/Rhesus macaque PRLR siRNA oligo Duplex | 699369 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101444 | Pre-made Cat/Feline PRLR siRNA oligo Duplex | 101101444 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479363 | Pre-made Dog/Canine PRLR siRNA oligo Duplex | 479363 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281422 | Pre-made Bovines/Cattle PRLR/SPRLR siRNA oligo Duplex | 281422 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053793 | Pre-made Equine/Horse PRLR siRNA oligo Duplex | 100053793 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRLR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26226-Ab | Human | Anti-Human PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26226-Ab | Rat | Anti-Rat PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26226-Ab | Mouse | Anti-Mouse PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26226-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26226-Ab | Cat/Feline | Anti-Cat/Feline PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26226-Ab | Dog/Canine | Anti-Dog/Canine PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26226-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26226-Ab | Equine/Horse | Anti-Equine/Horse PRLR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PRLR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26226-Ag | Human | Human PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T26226-Ag | Rat | Rat PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T26226-Ag | Mouse | Mouse PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T26226-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T26226-Ag | Cat/Feline | Cat/Feline PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T26226-Ag | Dog/Canine | Dog/Canine PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T26226-Ag | Bovines/Cattle | Bovines/Cattle PRLR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T26226-Ag | Equine/Horse | Equine/Horse PRLR VLP (virus-like particle) | HEK293 | Products Developing |
