Explore Fibrinogen Gamma Chain/FGG gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
| Target ID |
GM-T26144
|
| Target Name |
Fibrinogen Gamma Chain/FGG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2266
|
| Gene ID |
100147221 (Equus caballus), 101092680 (Felis catus), 2266 (Homo sapiens), 24367 (Rattus norvegicus)
280792 (Bos taurus), 475474 (Canis lupus familiaris), 698363 (Macaca mulatta), 99571 (Mus musculus)
|
| Target Alternative Names |
3010002H13Rik,FGG,Fgg,Fibrinogen Gamma Chain,Fibrinogen gamma chain
|
| Uniprot Accession |
P02679,P02680,P12799,P12800,Q8VCM7
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
Malignant neoplasm of colon, Acute pancreatitis, Malignant neoplasm of bladder
|
| Disease from KEGG |
Complement and coagulation cascades, Platelet activation, Staphylococcus aureus infection
|
| Gene Ensembl |
ENSECAG00000008280, ENSG00000171557, ENSBTAG00000006745, ENSCAFG00845009858, ENSMMUG00000021304, ENSMUSG00000033860
|
Pre-made viral vector of Fibrinogen Gamma Chain/FGG cDNA Clones/ORF Plasmid
Fibrinogen Gamma Chain/FGG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2266 | Pre-made Human FGG siRNA oligo Duplex | 2266 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24367 | Pre-made Rat Fgg siRNA oligo Duplex | 24367 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo99571 | Pre-made Mouse Fgg/3010002H13Rik siRNA oligo Duplex | 99571 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698363 | Pre-made Cynomolgus/Rhesus macaque FGG siRNA oligo Duplex | 698363 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092680 | Pre-made Cat/Feline FGG siRNA oligo Duplex | 101092680 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475474 | Pre-made Dog/Canine FGG siRNA oligo Duplex | 475474 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280792 | Pre-made Bovines/Cattle FGG siRNA oligo Duplex | 280792 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100147221 | Pre-made Equine/Horse FGG siRNA oligo Duplex | 100147221 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Fibrinogen Gamma Chain/FGG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T26144-Ab | Human | Anti-Human Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T26144-Ab | Rat | Anti-Rat Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T26144-Ab | Mouse | Anti-Mouse Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T26144-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T26144-Ab | Cat/Feline | Anti-Cat/Feline Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T26144-Ab | Dog/Canine | Anti-Dog/Canine Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T26144-Ab | Bovines/Cattle | Anti-Bovines/Cattle Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T26144-Ab | Equine/Horse | Anti-Equine/Horse Fibrinogen Gamma Chain/FGG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Fibrinogen Gamma Chain/FGG VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T26144-Ag | Human | Human Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T26144-Ag | Rat | Rat Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T26144-Ag | Mouse | Mouse Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T26144-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T26144-Ag | Cat/Feline | Cat/Feline Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T26144-Ag | Dog/Canine | Dog/Canine Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T26144-Ag | Bovines/Cattle | Bovines/Cattle Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T26144-Ag | Equine/Horse | Equine/Horse Fibrinogen Gamma Chain/FGG VLP (virus-like particle) | HEK293 | Products Developing |
