Explore LOXL2 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T25637
|
| Target Name |
LOXL2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4017
|
| Gene ID |
100058083 (Equus caballus), 101084102 (Felis catus), 290350 (Rattus norvegicus), 4017 (Homo sapiens) 486118 (Canis lupus familiaris), 532684 (Bos taurus), 710151 (Macaca mulatta)
|
| Target Alternative Names |
LOR,LOR2,LOXL2,Loxl2,Lysyl oxidase homolog 2,Lysyl oxidase-like protein 2,Lysyl oxidase-related protein 2,Lysyl oxidase-related protein WS9-14,WS9-14
|
| Uniprot Accession |
B5DF27,Q9Y4K0,A6H737
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, INN Index
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000025038, ENSG00000134013, ENSCAFG00845017019, ENSBTAG00000006214, ENSMMUG00000050549
|
Pre-made viral vector of LOXL2 cDNA Clones/ORF Plasmid
LOXL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4017 | Pre-made Human LOXL2/LOR/LOR2 siRNA oligo Duplex | 4017 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo290350 | Pre-made Rat Loxl2 siRNA oligo Duplex | 290350 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710151 | Pre-made Cynomolgus/Rhesus macaque LOXL2 siRNA oligo Duplex | 710151 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084102 | Pre-made Cat/Feline LOXL2 siRNA oligo Duplex | 101084102 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486118 | Pre-made Dog/Canine LOXL2 siRNA oligo Duplex | 486118 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532684 | Pre-made Bovines/Cattle LOXL2 siRNA oligo Duplex | 532684 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058083 | Pre-made Equine/Horse LOXL2 siRNA oligo Duplex | 100058083 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LOXL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T25637-Ab | Human | Anti-Human LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T25637-Ab | Rat | Anti-Rat LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T25637-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T25637-Ab | Cat/Feline | Anti-Cat/Feline LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T25637-Ab | Dog/Canine | Anti-Dog/Canine LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T25637-Ab | Bovines/Cattle | Anti-Bovines/Cattle LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T25637-Ab | Equine/Horse | Anti-Equine/Horse LOXL2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LOXL2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T25637-Ag | Human | Human LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T25637-Ag | Rat | Rat LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T25637-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T25637-Ag | Cat/Feline | Cat/Feline LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T25637-Ag | Dog/Canine | Dog/Canine LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T25637-Ag | Bovines/Cattle | Bovines/Cattle LOXL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T25637-Ag | Equine/Horse | Equine/Horse LOXL2 recombinant protein | Mammalian cell | Detail |