Explore CXCR3B/CXCR3/CD183 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]
| Target ID |
GM-T25315
|
| Target Name |
CXCR3B/CXCR3/CD183
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2833
|
| Gene ID |
100056190 (Equus caballus), 101094573 (Felis catus), 12766 (Mus musculus), 2833 (Homo sapiens)
491952 (Canis lupus familiaris), 497018 (Bos taurus), 699438 (Macaca mulatta), 84475 (Rattus norvegicus)
|
| Target Alternative Names |
C-X-C chemokine receptor type 3,CD182,CD183,CKR-L2,CMKAR3,CXC-R3,CXCR-3,CXCR3,CXCR3B,Cd183,Cmkar3,Cxcr3,G protein-coupled receptor 9,GPR9,Gpr9,IP10-R,Interferon-inducible protein 10 receptor (IP-10 receptor),Mig-R,MigR
|
| Uniprot Accession |
O88410,P49682,Q5KSK8,Q5MD61,Q9JII9
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000023587, ENSMUSG00000050232, ENSG00000186810, ENSCAFG00845019157, ENSBTAG00000014798
|
| Target Classification |
GPCR, Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of CXCR3B/CXCR3/CD183 cDNA Clones/ORF Plasmid
CXCR3B/CXCR3/CD183 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2833 | Pre-made Human CXCR3/GPR9/MigR siRNA oligo Duplex | 2833 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo84475 | Pre-made Rat Cxcr3/Gpr9 siRNA oligo Duplex | 84475 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12766 | Pre-made Mouse Cxcr3/Cd183/Cmkar3 siRNA oligo Duplex | 12766 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699438 | Pre-made Cynomolgus/Rhesus macaque CXCR3 siRNA oligo Duplex | 699438 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094573 | Pre-made Cat/Feline CXCR3 siRNA oligo Duplex | 101094573 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491952 | Pre-made Dog/Canine CXCR3 siRNA oligo Duplex | 491952 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo497018 | Pre-made Bovines/Cattle CXCR3 siRNA oligo Duplex | 497018 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056190 | Pre-made Equine/Horse CXCR3 siRNA oligo Duplex | 100056190 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CXCR3B/CXCR3/CD183 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T25315-Ab | Human | Anti-Human CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-T25315-Ab | Rat | Anti-Rat CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-T25315-Ab | Mouse | Anti-Mouse CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-T25315-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-T25315-Ab | Cat/Feline | Anti-Cat/Feline CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-T25315-Ab | Dog/Canine | Anti-Dog/Canine CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-T25315-Ab | Bovines/Cattle | Anti-Bovines/Cattle CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-T25315-Ab | Equine/Horse | Anti-Equine/Horse CXCR3B/CXCR3/CD183 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
CXCR3B/CXCR3/CD183 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T25315-Ag | Human | Human CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T25315-Ag | Rat | Rat CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T25315-Ag | Mouse | Mouse CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T25315-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T25315-Ag | Cat/Feline | Cat/Feline CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T25315-Ag | Dog/Canine | Dog/Canine CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T25315-Ag | Bovines/Cattle | Bovines/Cattle CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T25315-Ag | Equine/Horse | Equine/Horse CXCR3B/CXCR3/CD183 VLP (virus-like particle) | HEK293 | Products Developing |
