Explore CACNA1S gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T24965
|
| Target Name |
CACNA1S
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
779
|
| Gene ID |
100034092 (Equus caballus), 100337204 (Bos taurus), 12292 (Mus musculus), 490244 (Canis lupus familiaris)
654399 (Felis catus), 682930 (Rattus norvegicus), 708706 (Macaca mulatta), 779 (Homo sapiens)
|
| Target Alternative Names |
CACNA1S,CACNL1A3,CCHL1A3,CMYO18,CMYP18,Cacna1s,Calcium channel,Cav1.1,Cchl1a3,DHPR,DHPR alpha1s,DHPRM,HOKPP,HOKPP1,L type,MHS5,RGD1565743,TTPP1,Voltage-dependent L-type calcium channel subunit alpha-1S,Voltage-gated calcium channel subunit alpha Cav1.1,alpha-1 polypeptide,caV1.1,fmd,hypoPP,isoform 3,mdg,sj,skeletal muscle
|
| Uniprot Accession |
Q02789,Q02485,Q13698
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Adrenergic signaling in cardiomyocytes, Vascular smooth muscle contraction, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Insulin secretion, GnRH signaling pathway, Oxytocin signaling pathway, Renin secretion, Aldosterone synthesis and secretion, Cortisol synthesis and secretion, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Chemical carcinogenesis - receptor activation, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000018762, ENSBTAG00000047491, ENSMUSG00000026407, ENSCAFG00845019094, ENSMMUG00000017414, ENSG00000081248
|
| Target Classification |
|
CACNA1S siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo779 | Pre-made Human CACNA1S/MHS5/DHPRM siRNA oligo Duplex | 779 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo682930 | Pre-made Rat Cacna1s/Cchl1a3/RGD1565743 siRNA oligo Duplex | 682930 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12292 | Pre-made Mouse Cacna1s/sj/fmd siRNA oligo Duplex | 12292 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708706 | Pre-made Cynomolgus/Rhesus macaque CACNA1S siRNA oligo Duplex | 708706 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo654399 | Pre-made Cat/Feline CACNA1S siRNA oligo Duplex | 654399 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490244 | Pre-made Dog/Canine CACNA1S siRNA oligo Duplex | 490244 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100337204 | Pre-made Bovines/Cattle CACNA1S/caV1.1 siRNA oligo Duplex | 100337204 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034092 | Pre-made Equine/Horse CACNA1S siRNA oligo Duplex | 100034092 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CACNA1S antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T24965-Ab | Human | Anti-Human CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T24965-Ab | Rat | Anti-Rat CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T24965-Ab | Mouse | Anti-Mouse CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T24965-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T24965-Ab | Cat/Feline | Anti-Cat/Feline CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T24965-Ab | Dog/Canine | Anti-Dog/Canine CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T24965-Ab | Bovines/Cattle | Anti-Bovines/Cattle CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T24965-Ab | Equine/Horse | Anti-Equine/Horse CACNA1S monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CACNA1S VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T24965-Ag | Human | Human CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T24965-Ag | Rat | Rat CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T24965-Ag | Mouse | Mouse CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T24965-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T24965-Ag | Cat/Feline | Cat/Feline CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T24965-Ag | Dog/Canine | Dog/Canine CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T24965-Ag | Bovines/Cattle | Bovines/Cattle CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T24965-Ag | Equine/Horse | Equine/Horse CACNA1S VLP (virus-like particle) | HEK293 | Products Developing |
