Explore CAD gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
| Target ID |
GM-T24548
|
| Target Name |
CAD
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
790
|
| Gene ID |
100055366 (Equus caballus), 101091102 (Felis catus), 24240 (Rattus norvegicus), 483009 (Canis lupus familiaris)
504261 (Bos taurus), 69719 (Mus musculus), 699460 (Macaca mulatta), 790 (Homo sapiens)
|
| Target Alternative Names |
2410008J01Rik,CAD,CDG1Z,Cad,Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase,Cpad,DEE50,EIEE50,GATD4,Multifunctional protein CAD
|
| Uniprot Accession |
B2RQC6,P27708
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000014690, ENSCAFG00845006464, ENSBTAG00000017894, ENSMUSG00000013629, ENSMMUG00000010269, ENSG00000084774
|
Pre-made viral vector of CAD cDNA Clones/ORF Plasmid
CAD siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo790 | Pre-made Human CAD/CDG1Z/DEE50 siRNA oligo Duplex | 790 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24240 | Pre-made Rat Cad siRNA oligo Duplex | 24240 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo69719 | Pre-made Mouse Cad/Cpad/2410008J01Rik siRNA oligo Duplex | 69719 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699460 | Pre-made Cynomolgus/Rhesus macaque CAD siRNA oligo Duplex | 699460 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091102 | Pre-made Cat/Feline CAD siRNA oligo Duplex | 101091102 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483009 | Pre-made Dog/Canine CAD siRNA oligo Duplex | 483009 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504261 | Pre-made Bovines/Cattle CAD siRNA oligo Duplex | 504261 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055366 | Pre-made Equine/Horse CAD siRNA oligo Duplex | 100055366 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CAD antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T24548-Ab | Human | Anti-Human CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T24548-Ab | Rat | Anti-Rat CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T24548-Ab | Mouse | Anti-Mouse CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T24548-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T24548-Ab | Cat/Feline | Anti-Cat/Feline CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T24548-Ab | Dog/Canine | Anti-Dog/Canine CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T24548-Ab | Bovines/Cattle | Anti-Bovines/Cattle CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T24548-Ab | Equine/Horse | Anti-Equine/Horse CAD monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CAD recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T24548-Ag | Human | Human CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T24548-Ag | Rat | Rat CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T24548-Ag | Mouse | Mouse CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T24548-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T24548-Ag | Cat/Feline | Cat/Feline CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T24548-Ag | Dog/Canine | Dog/Canine CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T24548-Ag | Bovines/Cattle | Bovines/Cattle CAD recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T24548-Ag | Equine/Horse | Equine/Horse CAD recombinant protein | Mammalian cell | Detail |
