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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
| Target ID |
GM-T23666
|
| Target Name |
AHR
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
196
|
| Gene ID |
100066186 (Equus caballus), 101084947 (Felis catus), 11622 (Mus musculus), 196 (Homo sapiens) 25690 (Rattus norvegicus), 280714 (Bos taurus), 475251 (Canis lupus familiaris), 714254 (Macaca mulatta)
|
| Target Alternative Names |
AHR,Ah,Ah receptor,AhR,Ahh,Ahr,Ahre,Aryl hydrocarbon receptor,Class E basic helix-loop-helix protein 76 (bHLHe76),FVH3,In,RP85,bHLHe76
|
| Uniprot Accession |
P30561,Q8R4S5,Q8R4S6,P35869,P41738
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Th17 cell differentiation, Cushing syndrome, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000013393, ENSMUSG00000019256, ENSG00000106546, ENSBTAG00000007746, ENSCAFG00845005867, ENSMMUG00000012203
|
Pre-made viral vector of AHR cDNA Clones/ORF Plasmid
AHR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo196 | Pre-made Human AHR/FVH3/RP85 siRNA oligo Duplex | 196 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25690 | Pre-made Rat Ahr siRNA oligo Duplex | 25690 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11622 | Pre-made Mouse Ahr/Ah/In siRNA oligo Duplex | 11622 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714254 | Pre-made Cynomolgus/Rhesus macaque AHR siRNA oligo Duplex | 714254 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084947 | Pre-made Cat/Feline AHR siRNA oligo Duplex | 101084947 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475251 | Pre-made Dog/Canine AHR siRNA oligo Duplex | 475251 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280714 | Pre-made Bovines/Cattle AHR siRNA oligo Duplex | 280714 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066186 | Pre-made Equine/Horse AHR siRNA oligo Duplex | 100066186 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
AHR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23666-Ab | Human | Anti-Human AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T23666-Ab | Rat | Anti-Rat AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T23666-Ab | Mouse | Anti-Mouse AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T23666-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T23666-Ab | Cat/Feline | Anti-Cat/Feline AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T23666-Ab | Dog/Canine | Anti-Dog/Canine AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T23666-Ab | Bovines/Cattle | Anti-Bovines/Cattle AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T23666-Ab | Equine/Horse | Anti-Equine/Horse AHR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
AHR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23666-Ag | Human | Human AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T23666-Ag | Rat | Rat AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T23666-Ag | Mouse | Mouse AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T23666-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T23666-Ag | Cat/Feline | Cat/Feline AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T23666-Ag | Dog/Canine | Dog/Canine AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T23666-Ag | Bovines/Cattle | Bovines/Cattle AHR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T23666-Ag | Equine/Horse | Equine/Horse AHR recombinant protein | Mammalian cell | Detail |