Explore PRKG2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein binds to and inhibits the activation of several receptor tyrosine kinases. The membrane-bound protein is a regulator of intestinal secretion, bone growth and renin secretion. Alternate splicing results in multiple transcript variants encoding distinct isoforms whose regulatory N-termini differ in length but whose C-terminal catalytic domains are identical. [provided by RefSeq, May 2018]
Target ID |
GM-T23606
|
Target Name |
PRKG2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5593
|
Gene ID |
100060358 (Equus caballus), 100855930 (Canis lupus familiaris), 101091618 (Felis catus), 19092 (Mus musculus) 25523 (Rattus norvegicus), 533330 (Bos taurus), 5593 (Homo sapiens), 696308 (Macaca mulatta)
|
Target Alternative Names |
PRKG2,Prkg2,CGKII,Prkgr2,cGK-II,cGKII,GDPKII,AMD4,PKG2,SMDP,cGK2,PRKGR2
|
Uniprot Accession |
Q61410,Q64595,Q13237
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
cGMP-PKG signaling pathway, Gap junction, Platelet activation, Circadian entrainment, Olfactory transduction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion
|
Gene Ensembl |
ENSECAG00000024387, ENSCAFG00845018088, ENSMUSG00000029334, ENSBTAG00000002978, ENSG00000138669, ENSMMUG00000019859
|
Target Classification |
Kinase
|
PRKG2 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo5593 | Pre-made Human PRKG2/AMD4/PKG2 siRNA oligo Duplex | 5593 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo25523 | Pre-made Rat Prkg2/cGKII/GDPKII siRNA oligo Duplex | 25523 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo19092 | Pre-made Mouse Prkg2/CGKII/Prkgr2 siRNA oligo Duplex | 19092 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo696308 | Pre-made Cynomolgus/Rhesus macaque PRKG2 siRNA oligo Duplex | 696308 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101091618 | Pre-made Cat/Feline PRKG2 siRNA oligo Duplex | 101091618 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo100855930 | Pre-made Dog/Canine PRKG2 siRNA oligo Duplex | 100855930 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo533330 | Pre-made Bovines/Cattle PRKG2 siRNA oligo Duplex | 533330 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100060358 | Pre-made Equine/Horse PRKG2 siRNA oligo Duplex | 100060358 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRKG2 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T23606-Ab | Human | Anti-Human PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T23606-Ab | Rat | Anti-Rat PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T23606-Ab | Mouse | Anti-Mouse PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T23606-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T23606-Ab | Cat/Feline | Anti-Cat/Feline PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T23606-Ab | Dog/Canine | Anti-Dog/Canine PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T23606-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T23606-Ab | Equine/Horse | Anti-Equine/Horse PRKG2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PRKG2 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T23606-Ag | Human | Human PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T23606-Ag | Rat | Rat PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T23606-Ag | Mouse | Mouse PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T23606-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T23606-Ag | Cat/Feline | Cat/Feline PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T23606-Ag | Dog/Canine | Dog/Canine PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T23606-Ag | Bovines/Cattle | Bovines/Cattle PRKG2 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T23606-Ag | Equine/Horse | Equine/Horse PRKG2 recombinant protein | Mammalian cell | Detail |