Explore EDNRA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
| Target ID |
GM-T23499
|
| Target Name |
EDNRA
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1909
|
| Gene ID |
100062644 (Equus caballus), 101083419 (Felis catus), 13617 (Mus musculus), 1909 (Homo sapiens)
24326 (Rattus norvegicus), 281749 (Bos taurus), 450187 (Canis lupus familiaris), 704135 (Macaca mulatta)
|
| Target Alternative Names |
EDNRA,Ednra,ETa,ET-AR,AEA001,Gpcr10,Mhdaaea1,ETA,ET-A,ETAR,ETRA,MFDA,ETA-R,hET-AR,Eta,Endor,RGD1559432
|
| Uniprot Accession |
Q61614,P25101,P26684,P21450,Q5KSU9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
Calcium signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction, Renin secretion, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000019798, ENSMUSG00000031616, ENSG00000151617, ENSBTAG00000013674, ENSCAFG00845013340, ENSMMUG00000003659
|
| Target Classification |
GPCR
|
Pre-made viral vector of EDNRA cDNA Clones/ORF Plasmid
EDNRA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1909 | Pre-made Human EDNRA/ETA/ET-A siRNA oligo Duplex | 1909 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24326 | Pre-made Rat Ednra/Eta/ET-A siRNA oligo Duplex | 24326 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13617 | Pre-made Mouse Ednra/ETa/ET-AR siRNA oligo Duplex | 13617 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704135 | Pre-made Cynomolgus/Rhesus macaque EDNRA siRNA oligo Duplex | 704135 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083419 | Pre-made Cat/Feline EDNRA siRNA oligo Duplex | 101083419 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo450187 | Pre-made Dog/Canine EDNRA siRNA oligo Duplex | 450187 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281749 | Pre-made Bovines/Cattle EDNRA siRNA oligo Duplex | 281749 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062644 | Pre-made Equine/Horse EDNRA siRNA oligo Duplex | 100062644 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
EDNRA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23499-Ab | Human | Anti-Human EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T23499-Ab | Rat | Anti-Rat EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T23499-Ab | Mouse | Anti-Mouse EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T23499-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T23499-Ab | Cat/Feline | Anti-Cat/Feline EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T23499-Ab | Dog/Canine | Anti-Dog/Canine EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T23499-Ab | Bovines/Cattle | Anti-Bovines/Cattle EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T23499-Ab | Equine/Horse | Anti-Equine/Horse EDNRA monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
EDNRA VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23499-Ag | Human | Human EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T23499-Ag | Rat | Rat EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T23499-Ag | Mouse | Mouse EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T23499-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T23499-Ag | Cat/Feline | Cat/Feline EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T23499-Ag | Dog/Canine | Dog/Canine EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T23499-Ag | Bovines/Cattle | Bovines/Cattle EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T23499-Ag | Equine/Horse | Equine/Horse EDNRA VLP (virus-like particle) | HEK293 | Products Developing |
