Explore STEAP2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T23485
|
| Target Name |
STEAP2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
261729
|
| Gene ID |
100050610 (Equus caballus), 101080957 (Felis catus), 106997549 (Macaca mulatta), 261729 (Homo sapiens)
312052 (Rattus norvegicus), 482291 (Canis lupus familiaris), 504616 (Bos taurus), 74051 (Mus musculus)
|
| Target Alternative Names |
4921538B17Rik,IPCA-1,IPCA1,Metalloreductase STEAP2,PCANAP1,PUMPCn,Prostate cancer-associated protein 1,Protein up-regulated in metastatic prostate cancer (PUMPCn),STAMP1,STEAP2,STMP,Six-transmembrane epithelial antigen of prostate 2,SixTransMembrane protein of prostate 1,Steap2
|
| Uniprot Accession |
Q8NFT2,Q8BWB6
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Mineral absorption
|
| Gene Ensembl |
ENSECAG00000007108, ENSMMUG00000023653, ENSG00000157214, ENSBTAG00000003506, ENSMUSG00000015653
|
| Target Classification |
Tumor-associated antigen (TAA)
|
STEAP2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo261729 | Pre-made Human STEAP2/STMP/IPCA1 siRNA oligo Duplex | 261729 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo312052 | Pre-made Rat Steap2 siRNA oligo Duplex | 312052 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74051 | Pre-made Mouse Steap2/STMP/IPCA1 siRNA oligo Duplex | 74051 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106997549 | Pre-made Cynomolgus/Rhesus macaque STEAP2 siRNA oligo Duplex | 106997549 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080957 | Pre-made Cat/Feline STEAP2 siRNA oligo Duplex | 101080957 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482291 | Pre-made Dog/Canine STEAP2 siRNA oligo Duplex | 482291 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo504616 | Pre-made Bovines/Cattle STEAP2 siRNA oligo Duplex | 504616 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050610 | Pre-made Equine/Horse STEAP2 siRNA oligo Duplex | 100050610 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
STEAP2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23485-Ab | Human | Anti-Human STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T23485-Ab | Rat | Anti-Rat STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T23485-Ab | Mouse | Anti-Mouse STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T23485-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T23485-Ab | Cat/Feline | Anti-Cat/Feline STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T23485-Ab | Dog/Canine | Anti-Dog/Canine STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T23485-Ab | Bovines/Cattle | Anti-Bovines/Cattle STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T23485-Ab | Equine/Horse | Anti-Equine/Horse STEAP2 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
STEAP2 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23485-Ag | Human | Human STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-T23485-Ag | Rat | Rat STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-T23485-Ag | Mouse | Mouse STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-T23485-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-T23485-Ag | Cat/Feline | Cat/Feline STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-T23485-Ag | Dog/Canine | Dog/Canine STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-T23485-Ag | Bovines/Cattle | Bovines/Cattle STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-T23485-Ag | Equine/Horse | Equine/Horse STEAP2 VLP (virus-like particle) | HEK293 | Products Developing |
