Explore MPO gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
| Target ID |
GM-T23471
|
| Target Name |
MPO
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4353
|
| Gene ID |
100070920 (Equus caballus), 100142673 (Felis catus), 17523 (Mus musculus), 303413 (Rattus norvegicus)
4353 (Homo sapiens), 511206 (Bos taurus), 609986 (Canis lupus familiaris), 714246 (Macaca mulatta)
|
| Target Alternative Names |
MPO,Mpo,Myeloperoxidase,mKIAA4033
|
| Uniprot Accession |
P11247,P05164
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Disease |
Ovary Cancer, prolonged cough, Eosinophilic airway inflammation, lung function assessment, Asthma, Congenital occlusion of ureteropelvic junction, Dent disease, Cardiovascular disease, Cystic fibrosis
|
| Disease from KEGG |
Phagosome, Acute myeloid leukemia
|
| Gene Ensembl |
ENSECAG00000006662, ENSMUSG00000009350, ENSG00000005381, ENSBTAG00000011616, ENSCAFG00845018435, ENSMMUG00000002266
|
MPO siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4353 | Pre-made Human MPO siRNA oligo Duplex | 4353 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo303413 | Pre-made Rat Mpo siRNA oligo Duplex | 303413 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17523 | Pre-made Mouse Mpo/mKIAA4033 siRNA oligo Duplex | 17523 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714246 | Pre-made Cynomolgus/Rhesus macaque MPO siRNA oligo Duplex | 714246 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100142673 | Pre-made Cat/Feline MPO siRNA oligo Duplex | 100142673 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo609986 | Pre-made Dog/Canine MPO siRNA oligo Duplex | 609986 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo511206 | Pre-made Bovines/Cattle MPO siRNA oligo Duplex | 511206 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070920 | Pre-made Equine/Horse MPO siRNA oligo Duplex | 100070920 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MPO antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T23471-Ab | Human | Anti-Human MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T23471-Ab | Rat | Anti-Rat MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T23471-Ab | Mouse | Anti-Mouse MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T23471-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T23471-Ab | Cat/Feline | Anti-Cat/Feline MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T23471-Ab | Dog/Canine | Anti-Dog/Canine MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T23471-Ab | Bovines/Cattle | Anti-Bovines/Cattle MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T23471-Ab | Equine/Horse | Anti-Equine/Horse MPO monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
MPO recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T23471-Ag | Human | Human MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T23471-Ag | Rat | Rat MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T23471-Ag | Mouse | Mouse MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T23471-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T23471-Ag | Cat/Feline | Cat/Feline MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T23471-Ag | Dog/Canine | Dog/Canine MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T23471-Ag | Bovines/Cattle | Bovines/Cattle MPO recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T23471-Ag | Equine/Horse | Equine/Horse MPO recombinant protein | Mammalian cell | Detail |
